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食物中的植物雌激素含量。

Phytoestrogen content in foods.

作者信息

Mazur W

机构信息

Folkhälsan Research Center, Department of Clinical Chemistry, University of Helsinki, Finland.

出版信息

Baillieres Clin Endocrinol Metab. 1998 Dec;12(4):729-42. doi: 10.1016/s0950-351x(98)80013-x.

Abstract

Plants abound in essential phytochemicals produced for their various vital functions. The same compounds seem also to be crucial for human health and disease. Recent human epidemiological and laboratory animal and cell studies on cancer and heart disease have highlighted the phytoestrogens--naturally occurring principles that share with steroidal oestrogens an ability to activate oestrogen receptors. The best known non-steroidal phytoestrogens include the isoflavones daidzein, genistein, formononetin and biochanin A, the coumestan coumestrol, and the lignans secoisolariciresinol and matairesinol. Acknowledging the potentially chemoprotective role of these non-nutrients, we have quantified all biologically important isoflavonoids and lignans in cereals, oilseeds and nuts, legumes, vegetables, fruits, berries and beverages such as tea, coffee and wine. In this chapter, we present a review of our studies on staple plant foods, indicating that plants contain, besides a wide range of chemicals with a number of biological properties, biologically active phytoestrogens--precursors of hormone-like compounds found in mammalian systems.

摘要

植物富含为其各种重要功能而产生的必需植物化学物质。同样的化合物似乎对人类健康和疾病也至关重要。最近关于癌症和心脏病的人类流行病学、实验室动物及细胞研究突出了植物雌激素——一种与甾体雌激素一样具有激活雌激素受体能力的天然物质。最知名的非甾体植物雌激素包括异黄酮大豆苷元、染料木黄酮、芒柄花黄素和鹰嘴豆芽素A,香豆雌酚,以及木脂素开环异落叶松脂素和matairesinol。认识到这些非营养物质潜在的化学保护作用后,我们对谷物、油籽、坚果、豆类、蔬菜、水果、浆果以及茶、咖啡和葡萄酒等饮料中的所有具有生物学重要性的异黄酮和木脂素进行了定量分析。在本章中,我们对主食植物性食物的研究进行了综述,表明植物除了含有多种具有多种生物学特性的化学物质外,还含有具有生物活性的植物雌激素——哺乳动物系统中发现的激素样化合物的前体。

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