Farooqui M A, Berenson C, Lohr J W
Department of Medicine, State University of New York at Buffalo and Veterans Administration Medical Center, 14215, USA.
Transplantation. 1999 Jun 15;67(11):1495-6. doi: 10.1097/00007890-199906150-00021.
Infections with atypical mycobacteria occur more frequently in patients with solid organ transplants than in the normal host.
We report a case of cutaneous Mycobacterium marinum infection in a renal transplant recipient. The patient presented with nodules on the forearm after returning from a fishing trip and was treated for cellulitis without success.
Cultures of a biopsy of the lesion grew M. marinum. The patient was treated with ethambutol and ciprofloxacin with a good response; however, 9 months of treatment were required for complete resolution.
Immunosuppressive therapy for renal transplantation increases susceptibility to a variety of opportunistic infections. A patient who presents with nodules on the extremities should be questioned regarding contact with fish, aquatic environments, or fish tank water, in which case infection with M. marinum should be considered. The diagnosis and treatment of this infection in transplant recipients is discussed.
与正常宿主相比,实体器官移植患者中不典型分枝杆菌感染更为常见。
我们报告一例肾移植受者皮肤海分枝杆菌感染病例。该患者钓鱼旅行归来后前臂出现结节,曾接受蜂窝织炎治疗但未成功。
病变活检培养出海分枝杆菌。患者接受乙胺丁醇和环丙沙星治疗,反应良好;然而,完全治愈需要9个月的治疗时间。
肾移植的免疫抑制治疗增加了对多种机会性感染的易感性。对于出现肢体结节的患者,应询问其是否接触过鱼类、水生环境或鱼缸水,这种情况下应考虑海分枝杆菌感染。本文讨论了移植受者中这种感染的诊断和治疗。