Okereke U N, Weber B E, Israel R H
Department of Internal Medicine, St Mary's Hospital, Rochester, NY, USA.
J Natl Med Assoc. 1999 Jun;91(6):357-9.
Spontaneous pneumomediastinum (SPM) is defined as pneumomediastinum in the absence of an underlying lung disease. It is the second most common cause of chest pain in young, healthy individuals (< 30 years) necessitating hospital visits. It is surpassed in frequency in this setting only by spontaneous pneumothorax. These two conditions may coexist in 18% of patients. The incidence of spontaneous pneumomediastinum varies in different communities and generally is relatively uncommon. Inhalational drug use (cocaine and cannabis) have been associated with a significant number of cases, although cases with no apparent etiologic or incriminating factors are well recognized. Also its recurrence, though uncommon, is worthy of note. It is a benign clinical condition with diverse clinical presentations. Physicians' knowledge of the presentation, treatment, and prognosis of SPM will guard against the need for expensive radiologic and laboratory tests. The differential diagnosis of chest pain, shortness of breath, and dysphagia include cardiac, pulmonary, and esophageal diseases. The tendency to pursue these entities may lead to laboratory investigations such as electrocardiograms, arterial blood gases, ventilation/perfusion scans, and contrast radiographic studies of the esophagus.
自发性纵隔气肿(SPM)定义为在无潜在肺部疾病情况下出现的纵隔气肿。它是年轻健康个体(<30岁)因胸痛需住院治疗的第二大常见原因。在这种情况下,其发病频率仅次于自发性气胸。这两种情况在18%的患者中可能同时存在。自发性纵隔气肿的发病率在不同社区有所不同,总体相对不常见。吸入性药物使用(可卡因和大麻)与大量病例相关,尽管无明显病因或可疑因素的病例也广为人知。此外,其复发虽不常见,但值得注意。它是一种具有多种临床表现的良性临床病症。医生对SPM的表现、治疗和预后的了解有助于避免进行昂贵的影像学和实验室检查。胸痛、气短和吞咽困难的鉴别诊断包括心脏、肺部和食管疾病。对这些疾病进行排查的倾向可能会导致进行诸如心电图、动脉血气分析、通气/灌注扫描以及食管造影等实验室检查。