Thirion X, Micallef J, Guet F, Delarozière J C, Arditti J, Huntsman A, Sanmarco J L, Lagier G
Centre collaborateur du C.E.I.P. de Marseille (PACA-Corse), Laboratoire de Santé Publique, Faculté de Médecine, France.
Therapie. 1999 Mar-Apr;54(2):243-9.
The aim of this study was to identify the latest trends in psychotropic drug use and the effect of the increase of maintenance treatments for serious opioid addiction. The results are based on data from OPPIDUM, an annual survey primarily concerned with the consumption of licit and illicit drugs. The study involved 1066 drug addicts recruited during the month of October 1997 from 38 French health centres connected with the Centres for Evaluation and Information on Drug Addiction (CEIP). The most frequently reported drugs were benzodiazepines (n = 323), some of which, especially flunitrazepam (Rohypnol, n = 123), are extremely addictive. The data showed a slight decrease in heroin consumption as well as a marked increase in the use of maintenance treatments. The association between benzodiazepines and buprenorphine (Subutex) should consequently be studied, whether buprenorphine is being used illicitly or prescribed as a maintenance treatment.
本研究的目的是确定精神药物使用的最新趋势以及严重阿片类药物成瘾维持治疗增加的影响。研究结果基于OPPIDUM的数据,这是一项主要关注合法和非法药物消费的年度调查。该研究涉及1997年10月从38个与药物成瘾评估和信息中心(CEIP)相关的法国健康中心招募的1066名吸毒者。报告最频繁的药物是苯二氮卓类药物(n = 323),其中一些,特别是氟硝西泮( Rohypnol,n = 123),极易成瘾。数据显示海洛因消费量略有下降,维持治疗的使用显著增加。因此,应研究苯二氮卓类药物与丁丙诺啡(舒布酮)之间的关联,无论丁丙诺啡是被非法使用还是作为维持治疗药物被处方使用。