Kopp P, Rumeau-Pichon C, Le Pen C
Université Paris I, Panthéon-Sorbonne.
Rev Epidemiol Sante Publique. 2000 Jun;48(3):256-70.
The development of maintenance treatment for subjects with addictive behavior is an important public health issue. As such, the social effectiveness of maintenance products must be examined from an economical and social point of view. This paper aims at presenting the financial costs involved in the use of Subutex, a product commercialized since 1996.
A complete typology of costs related to drug addiction and its consequences was set up. Some of these costs were estimated on the basis of data drawn from the literature. The cost of Subutex use for maintenance treatment was assessed and compared with the financial stakes including the potential reduction of the economic and social cost of drug addiction.
Monthly treatment cost of Subutex was 1252 FrF per drug abuser on maintenance treatment. By extrapolation, for a population of 40,000 drug abusers, the direct medical cost of Subutex during a course of maintenance treatment with general practitioner follow-up was estimated at 600 millions FrF. US data sources were applied to France to assess the cost of illnesses attributable to drug addiction. The cost reached 4.8 billions FrF. The cost of delinquency associated with drug addiction, which mostly concerns money laundered to purchase substances was an estimated 6.4 billions FrF. Finally, the cost of public anti-drug abuse programs was nearly 4.7 billions FrF. Thus, the direct cost of drug addiction consequences reached 15.6 billions FrF. This cost should be compared with the annual cost of Subutex for public organizations which was an estimated 600 millions FrF.
The "profit" threshold of maintenance treatment with Subutex in terms of direct costs is very low. A decrease of only 4% of the costs associated with drug addiction would make it possible to balance the financial budget for the community. Our analysis does not take into acount absolutely all the public health and safety aspects involved in the use of Subutex. It does however provide a useful assessment of the financial aspects of the question and justification for this therapeutic strategy from a budgetary point of view.
成瘾行为患者维持治疗的发展是一个重要的公共卫生问题。因此,必须从经济和社会角度审视维持治疗产品的社会效益。本文旨在阐述自1996年商业化的产品舒倍生(Subutex)使用过程中涉及的财务成本。
建立了与药物成瘾及其后果相关的完整成本类型。其中一些成本是根据文献数据估算的。评估了舒倍生用于维持治疗的成本,并与包括药物成瘾经济和社会成本潜在降低在内的财务利害关系进行了比较。
接受维持治疗的药物滥用者使用舒倍生的每月治疗成本为每名1252法国法郎。据推断,对于40000名药物滥用者群体,在全科医生随访的维持治疗过程中,舒倍生的直接医疗成本估计为6亿法国法郎。将美国数据源应用于法国以评估药物成瘾所致疾病的成本。该成本达48亿法国法郎。与药物成瘾相关的犯罪成本(主要涉及为购买毒品而洗钱)估计为64亿法国法郎。最后,公共禁毒计划的成本近47亿法国法郎。因此,药物成瘾后果的直接成本达156亿法国法郎。应将此成本与公共机构使用舒倍生的年度成本(估计为6亿法国法郎)进行比较。
就直接成本而言,舒倍生维持治疗的“盈利”门槛非常低。与药物成瘾相关成本仅降低4%就有可能平衡社区的财务预算。我们的分析并未绝对考虑使用舒倍生所涉及的所有公共卫生和安全方面。然而,它确实对该问题的财务方面进行了有益评估,并从预算角度为这一治疗策略提供了依据。