性传播疾病患者中人类嗜T淋巴细胞病毒I型和II型的血清阳性率较低。人类嗜T淋巴细胞病毒与性传播疾病研究组。

Low seroprevalence of HTLV-I and HTLV-II in patients with a sexually transmitted disease. Study Group for HTLV and STDs.

作者信息

Suligoi B, Galli C, Ciuta S, Decker R

机构信息

Istituto Superiore di Sanità, National AIDS Center, Rome, Italy.

出版信息

Eur J Epidemiol. 1999 Mar;15(3):225-9. doi: 10.1023/a:1007534600034.

DOI:10.1023/a:1007534600034

PMID:10395051

Abstract

To determine the prevalence of HTLV I-II among highly sexually active adults, a seroprevalence study was conducted in Italy between March 1992 and March 1993 among 1506 patients with a newly diagnosed STD. Individuals were tested with an enzyme immunoassay that employs a double viral lysate from HTLV-I and HTLV-II infected cell lines; confirmation and discrimination between HTLV-I and II were performed by a dot-blot immunoassay. One patient (0.07%) was confirmed HTLV-I positive and one (0.07%) HTLV-II positive. The HTLV-I positive was a Romanian woman, and the other was an intravenous drug user. The 0.13% HTLV prevalence observed in this study is intermediate between the 0.034% found among Italian blood donors and the 3.5-6% found among Italian intravenous drug users. These data suggest that there is not a high prevalence of these viruses among Italians with STDs.

摘要

为确定性活动频繁的成年人中人类嗜T淋巴细胞病毒I型和II型（HTLV I-II）的流行情况，1992年3月至1993年3月在意大利对1506例新诊断为性传播疾病（STD）的患者进行了血清流行率研究。采用酶免疫测定法对个体进行检测，该方法使用来自HTLV-I和HTLV-II感染细胞系的双重病毒裂解物；通过斑点印迹免疫测定法对HTLV-I和II进行确认和鉴别。一名患者（0.07%）被确认为HTLV-I阳性，一名（0.07%）为HTLV-II阳性。HTLV-I阳性患者是一名罗马尼亚女性，另一名是静脉吸毒者。本研究中观察到的0.13%的HTLV流行率介于意大利献血者中发现的0.034%和意大利静脉吸毒者中发现的3.5%-6%之间。这些数据表明，在患有性传播疾病的意大利人中，这些病毒的流行率并不高。