Funari M, Kavakama J, Shikanai-Yasuda M A, Castro L G, Bernard G, Rocha M S, Cerri G G, Müller N L
Department of Radiology, Hospital das Clínicas, University of São Paulo, SP, Brazil.
AJR Am J Roentgenol. 1999 Jul;173(1):59-64. doi: 10.2214/ajr.173.1.10397100.
To assess the pulmonary parenchymal findings on high-resolution CT in 41 patients with the chronic form of paracoccidioidomycosis (South American blastomycosis).
The study included 41 consecutive patients in whom chronic paracoccidioidomycosis had been proven. All patients underwent high-resolution CT (1-mm collimation, high-spatial-frequency reconstruction algorithm) at 12 equally spaced intervals through the chest. The images were analyzed by two radiologists, and each final decision was reached by consensus.
Thirty-eight (93%) of the 41 patients had CT scans with abnormal findings. The findings included interlobular septal thickening in 36 patients (88%), 1-25 mm diameter nodules in 34 (83%), peribronchovascular interstitial thickening in 32 (78%), centrilobular opacities in 26 (63%), intralobular lines in 24 (59%), ground-glass opacities in 14 (34%), cavitation in seven (17%), air-space consolidation in five (12%), traction bronchiectasis in 34 (83%), and paracicatricial emphysema in 28 (68%). In approximately 90% of patients, the abnormalities were bilateral and symmetrical and involved all lung zones.
High-resolution CT findings of paracoccidioidomycosis consist predominantly of interstitial abnormalities and nodules associated with traction bronchiectasis and paracicatricial emphysema in a bilaterally symmetrical distribution.
评估41例慢性副球孢子菌病（南美芽生菌病）患者的高分辨率CT肺实质表现。
该研究纳入了41例经证实患有慢性副球孢子菌病的连续患者。所有患者均接受胸部高分辨率CT检查（1毫米准直，高空间频率重建算法），扫描范围为胸部12个等间距层面。图像由两名放射科医生分析，最终诊断经双方达成共识。
41例患者中38例（93%）CT扫描有异常表现。这些表现包括36例（88%）小叶间隔增厚、34例（83%）直径1 - 25毫米的结节、32例（78%）支气管血管周围间质增厚、26例（63%）小叶中心性混浊、24例（59%）小叶内线、14例（34%）磨玻璃样混浊、7例（17%）空洞形成、5例（12%）气腔实变、34例（83%）牵拉性支气管扩张以及28例（68%）胸膜下瘢痕旁肺气肿。约90%的患者异常表现为双侧对称，累及所有肺叶。
副球孢子菌病的高分辨率CT表现主要为间质性异常和结节，伴有牵拉性支气管扩张和胸膜下瘢痕旁肺气肿，呈双侧对称分布。
