Foster J H, Peters T J
Department of Clinical Biochemistry, Kings College School of Medicine, London, United Kingdom.
Alcohol Clin Exp Res. 1999 Jun;23(6):1044-51.
There is very little work that has investigated the self-reported sleep status of alcohol misusers. This study addressed that imbalance.
The study consisted of two parts: 1) the outpatient study, a sample of DSM-IV alcohol-dependent subjects who were referred to an outpatient clinic and were given a series of questionnaires, including the Pittsburgh Sleep Quality Index (PSQI); and 2) the inpatient study, a group of DSM-IV alcohol-dependent subjects whose sleep was assessed by the Nottingham Health Profile (NHP) sleep subscore at the start of the study and again at the 12-week follow-up. Both the PSQI and NHP are self-report indices whereby higher scores indicate a poor sleep quality.
In the outpatient study, the PSQI scores were significantly higher in the alcoholics (n = 31) compared with the controls (n = 49). There were no differences in the PSQI scores among mildly (n = 11), moderately (n = 10), and severely (n = 11) dependent drinkers. The PSQI total scores correlated with the Beck Depression Index but not with severity of dependence or alcohol problem scores. Sleep latency emerged as the most significant predictor of relapse, and sleeping badly was associated with poor outcome at the 12-week follow-up in the inpatient study.
Self-reported sleep disturbance can provide clinicians with information to plan better treatment for alcohol misusers.
很少有研究调查过酒精滥用者自我报告的睡眠状况。本研究弥补了这一不足。
该研究包括两个部分:1)门诊研究,选取被转介至门诊诊所的DSM-IV酒精依赖受试者样本,让他们填写一系列问卷,包括匹兹堡睡眠质量指数(PSQI);2)住院研究,选取一组DSM-IV酒精依赖受试者,在研究开始时以及12周随访时通过诺丁汉健康量表(NHP)睡眠子量表评估他们的睡眠情况。PSQI和NHP均为自我报告指标,分数越高表明睡眠质量越差。
在门诊研究中,酗酒者(n = 31)的PSQI得分显著高于对照组(n = 49)。轻度(n = 11)、中度(n = 10)和重度(n = 11)依赖饮酒者的PSQI得分没有差异。PSQI总分与贝克抑郁量表相关,但与依赖程度或酒精问题得分无关。在住院研究中,入睡潜伏期是复发的最显著预测因素,睡眠不佳与12周随访时的不良预后相关。
自我报告的睡眠障碍可为临床医生提供信息,以便为酒精滥用者制定更好的治疗方案。