Couty F
Laboratoire de synthèse asymétrique, Université Pierre et Marie Curie, Paris, France.
Amino Acids. 1999;16(3-4):297-320. doi: 10.1007/BF01388174.
Results in the field of asymmetric synthesis of pipecolic acid derivatives are reviewed. Three sections describe the asymmetric syntheses of the title compounds (i) from the chiral pool (alpha-amino acids or carbohydrates) (ii) using a chiral auxiliary either derived from terpenes, alpha-amino acids, tartaric acid, an amine or beta-amino alcohols (iii) by means of asymmetric catalysis.
本文综述了哌啶酸衍生物不对称合成领域的研究成果。文章分为三个部分，分别描述了目标化合物的不对称合成方法：(i) 从手性源（α-氨基酸或碳水化合物）出发；(ii) 使用源自萜类、α-氨基酸、酒石酸、胺或β-氨基醇的手性助剂；(iii) 通过不对称催化。
