Trusov V V, Bazhenov A N, Stoliarov D D, Odnopozov I I
Ter Arkh. 1999;71(5):22-5.
Assessment of hemopheresis effects on calcium-regulating and immune systems, clinical and laboratory activity of rheumatoid arthritis (RA).
Hemosorption and plasmapheresis were included in combined treatment of 86 RA patients. Plasmapheresis was performed 3-5 days after hemosorption (a total of 4-6 procedures per course). The activity of RA, immune and calcium-regulating system were assessed clinically, with laboratory tests, enzyme immunoassay.
Hemosorption plus plasmapheresis produced positive effects on the disease course, activity. Laboratory indices improved. Percentage of T-helpers and T-suppressors, calcitonin loading rate, levels of parathormone, calcidiol normalized.
Combined hemopheresis therapy promotes correction of disorders in immune and calcium-regulating systems.
评估血液成分单采术对钙调节和免疫系统以及类风湿性关节炎（RA）临床和实验室活动的影响。
86例RA患者的联合治疗包括血液吸附和血浆置换。血浆置换在血液吸附后3 - 5天进行（每个疗程共4 - 6次操作）。通过临床评估、实验室检测、酶免疫测定评估RA、免疫和钙调节系统的活性。
血液吸附加血浆置换对病程和活动产生了积极影响。实验室指标得到改善。辅助性T细胞和抑制性T细胞百分比、降钙素负荷率、甲状旁腺激素水平、骨化二醇水平恢复正常。
联合血液成分单采术治疗有助于纠正免疫和钙调节系统的紊乱。
