Pagliaricci S, Lupattelli G, Mannarino E
Sezione di Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Università degli Studi di Perugia.
Ann Ital Med Int. 1999 Apr-Jun;14(2):124-6.
A 48-year-old female was referred to Perugia Hospital because of cardiac palpitations and insomnia. The clinical history, the physical examination and laboratory tests were supportive of hyperthyroidism. Since July 1994 the patient had been combating constipation by improper use of an iodine-containing antiseptic cream for external use only. She had inserted povidone-iodine into the rectum by means of a cannula. The iodine-containing cream was suspended, and a beta-blocker prescribed. Cardiac palpitations disappeared within 2 weeks, and plasma thyroid hormone levels returned to normal within 1 month. Hyperthyroidism in this patient was probably triggered by improper long-term use of an over-the-counter cream. When investigating the etiology of hyperthyroidism, a history of long-term use of iodine-containing medication should always be considered. These medications should be used with caution for only short periods of time and, if usage is prolonged, medical supervision should be recommended; above all, they should be applied only as directed.
一名48岁女性因心悸和失眠被转诊至佩鲁贾医院。临床病史、体格检查及实验室检查均支持甲状腺功能亢进症。自1994年7月起，该患者一直通过不当使用仅用于外用的含碘消毒乳膏来对抗便秘。她通过插管将聚维酮碘插入直肠。停用含碘乳膏，并开具了β受体阻滞剂。心悸在2周内消失，血浆甲状腺激素水平在1个月内恢复正常。该患者的甲状腺功能亢进症可能是由长期不当使用非处方药乳膏引发的。在调查甲状腺功能亢进症的病因时，应始终考虑长期使用含碘药物的病史。这些药物仅应在短时间内谨慎使用，若使用时间延长，应建议进行医学监测；最重要的是，应仅按指示使用。
