Zuberi S M, Matta N, Nawaz S, Stephenson J B, McWilliam R C, Hollman A
Fraser of Allander Neurosciences Unit, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK.
Neuromuscul Disord. 1999 Jun;9(4):203-7. doi: 10.1016/s0960-8966(99)00002-4.
One hundred paediatric, muscle ultrasound examinations performed in the evaluation of suspected neuromuscular disease were reviewed. The results were related to the presence or absence of neuromuscular disease in each child assessed. The group comprised 66 males and 34 females, age range 2 months to 16 years (mean 5.3 years). Scans were graded I-IV, according to muscle echogenicity, using Heckmatt's criteria. Thirty-two children had a final diagnosis of neuromuscular disease. The sensitivity of ultrasound in detecting neuromuscular disease was 78% with 91% specificity. The test was more reliable in the sub-group of > 3 years with a sensitivity of 81% and specificity of 96%. There was a significant difference in disease status, (with and without neuromuscular disease), between children with a normal, grade I, scan and those with an abnormal, grade II, III, IV, image (chi-square, P < 0.001, 95% confidence limits 0.54-0.86). Muscle ultrasound is a specific and sensitive investigation for suspected neuromuscular disease in children.
回顾了100例为评估疑似神经肌肉疾病而进行的儿科肌肉超声检查。结果与每个接受评估儿童是否患有神经肌肉疾病相关。该组包括66名男性和34名女性，年龄范围为2个月至16岁（平均5.3岁）。根据肌肉回声，采用赫克马特标准将扫描分为I-IV级。32名儿童最终被诊断为神经肌肉疾病。超声检测神经肌肉疾病的敏感性为78%，特异性为91%。该检测在3岁以上亚组中更可靠，敏感性为81%，特异性为96%。正常I级扫描的儿童与异常II级、III级、IV级图像的儿童在疾病状态（有无神经肌肉疾病）方面存在显著差异（卡方检验，P<0.001，95%置信区间0.54-0.86）。肌肉超声是儿童疑似神经肌肉疾病的一种特异性和敏感性检查。
