Ekdahl K, Persson K, Mölstad S, Melander E, Norrgren H, Söderström M, Hansson H B
Smittskyddsenheten i Malmö.
Lakartidningen. 1999 Jun 16;96(24):2962-5.
In an attempt to limit the spread of penicillin non-susceptible pneumococci (PNSP) in southern Sweden, early in 1995 an intervention project was launched, using a combination of traditional communicable disease control measures and actions aimed at reducing antibiotics consumption. Patients carrying PNSP (penicillin G MIC (0.5 mg/L) are monitored with nasopharyngeal cultures until PNSP-negative. Pre-school children are kept home from group day-care facilities. Previous antibiotic consumption was identified as a risk factor for PNSP carriage. Antibiotics sales decreased during the study period, and epidemiological findings suggest the dissemination of PNSP in the area to have been reduced by the intervention project.
为了限制瑞典南部对青霉素不敏感肺炎球菌（PNSP）的传播，1995年初启动了一项干预项目，该项目结合了传统的传染病控制措施以及旨在减少抗生素使用的行动。携带PNSP（青霉素G MIC≥0.5mg/L）的患者通过鼻咽培养进行监测，直至检测结果为PNSP阴性。学龄前儿童需居家，不前往集体日托机构。此前的抗生素使用被确定为携带PNSP的一个风险因素。在研究期间，抗生素销量下降，并且流行病学调查结果表明该干预项目已减少了该地区PNSP的传播。
