Lattuada E, Serretti A, Cusin C, Gasperini M, Smeraldi E
Istituto Scientifico H. San Raffaele, Department of Neuroscience, University of Milan, School of Medicine, Italy.
J Affect Disord. 1999 Jul;54(1-2):183-7. doi: 10.1016/s0165-0327(98)00141-4.
The aim of the present study is to evaluate the symptomatologic presentation of delusional compared to non-delusional major depressive episodes.
Two hundred and eighty-eight subjects suffering from mood disorder (144 bipolar, 133 unipolar) were assessed at admission by the Hamilton Depression Rating Scale (HAMD-21).
Depressive symptomatology was more severe in the delusional sample, even after the exclusion of the items directly involved with delusional symptoms (P = 0.00002).
Our data support the hypothesis of delusional depression as a more severe form of mood disorder.
本研究旨在评估妄想性与非妄想性重度抑郁发作的症状表现。
采用汉密尔顿抑郁评定量表（HAMD - 21）对288名患有情绪障碍的受试者（144名双相情感障碍患者，133名单相情感障碍患者）入院时进行评估。
即使排除与妄想症状直接相关的条目后，妄想性样本中的抑郁症状仍更为严重（P = 0.00002）。
我们的数据支持妄想性抑郁是一种更严重的情绪障碍形式这一假说。
