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精神病性抑郁与非精神病性抑郁的症状学分析

Symptomatologic analysis of psychotic and non-psychotic depression.

作者信息

Lattuada E, Serretti A, Cusin C, Gasperini M, Smeraldi E

机构信息

Istituto Scientifico H. San Raffaele, Department of Neuroscience, University of Milan, School of Medicine, Italy.

出版信息

J Affect Disord. 1999 Jul;54(1-2):183-7. doi: 10.1016/s0165-0327(98)00141-4.

Abstract

BACKGROUND

The aim of the present study is to evaluate the symptomatologic presentation of delusional compared to non-delusional major depressive episodes.

METHODS

Two hundred and eighty-eight subjects suffering from mood disorder (144 bipolar, 133 unipolar) were assessed at admission by the Hamilton Depression Rating Scale (HAMD-21).

RESULTS

Depressive symptomatology was more severe in the delusional sample, even after the exclusion of the items directly involved with delusional symptoms (P = 0.00002).

CONCLUSIONS

Our data support the hypothesis of delusional depression as a more severe form of mood disorder.

摘要

背景

本研究旨在评估妄想性与非妄想性重度抑郁发作的症状表现。

方法

采用汉密尔顿抑郁评定量表(HAMD - 21)对288名患有情绪障碍的受试者(144名双相情感障碍患者,133名单相情感障碍患者)入院时进行评估。

结果

即使排除与妄想症状直接相关的条目后,妄想性样本中的抑郁症状仍更为严重(P = 0.00002)。

结论

我们的数据支持妄想性抑郁是一种更严重的情绪障碍形式这一假说。

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