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酸茶(玫瑰茄)对原发性高血压的影响。

The effect of sour tea (Hibiscus sabdariffa) on essential hypertension.

作者信息

Haji Faraji M, Haji Tarkhani A

机构信息

Shaheed Beheshti University of Medical Sciences and Health Services, Eveen-Tehran, Iran.

出版信息

J Ethnopharmacol. 1999 Jun;65(3):231-6. doi: 10.1016/s0378-8741(98)00157-3.

Abstract

Considering the high prevalence of hypertension, its debilitating end organ damage, and the side effects of chemical drugs used for its treatment, we conducted this experimental study to evaluate the effect of sour tea (Hibiscus sabdariffa) on essential hypertension. For this purpose, 31 and 23 patients with moderate essential hypertension were randomly assigned to an experimental and control group, respectively. Patients with secondary hypertension or those consuming more than two drugs were excluded from the study. Systolic and diastolic blood pressures were measured before and 15 days after the intervention. In the experimental group, 45% of the patients were male and 55% were female, and the mean age was 52.6 +/- 7.9 years. In the control group, 30% of the patients were male, 70% were female, and the mean age of the patients was 51.5 +/- 10.1 years. Statistical findings showed an 11.2% lowering of the systolic blood pressure and a 10.7% decrease of diastolic pressure in the experimental group 12 days after beginning the treatment, as compared with the first day. The difference between the systolic blood pressures of the two groups was significant, as was the difference of the diastolic pressures of the two groups. Three days after stopping the treatment, systolic blood pressure was elevated by 7.9%, and diastolic pressure was elevated by 5.6% in the experimental and control groups. This difference between the two groups was also significant. This study proves the public belief and the results of in vitro studies concerning the effects of sour tea on lowering high blood pressure. More extensive studies on this subject are needed.

摘要

鉴于高血压的高患病率、其导致的使人衰弱的终末器官损害以及用于治疗的化学药物的副作用,我们开展了这项实验研究,以评估酸茶(玫瑰茄)对原发性高血压的影响。为此,分别将31例和23例中度原发性高血压患者随机分配至实验组和对照组。继发性高血压患者或服用两种以上药物的患者被排除在研究之外。在干预前和干预后15天测量收缩压和舒张压。实验组中,45%的患者为男性,55%为女性,平均年龄为52.6±7.9岁。对照组中,30%的患者为男性,70%为女性,患者的平均年龄为51.5±10.1岁。统计结果显示,与第一天相比,实验组在开始治疗12天后收缩压降低了11.2%,舒张压降低了10.7%。两组收缩压之间的差异显著,两组舒张压之间的差异也显著。停止治疗三天后,实验组和对照组的收缩压分别升高了7.9%,舒张压分别升高了5.6%。两组之间的这种差异也很显著。本研究证实了公众对于酸茶降低高血压作用的看法以及体外研究的结果。关于这个主题还需要进行更广泛的研究。

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