Al-Anbaki Marwah, Cavin Anne-Laure, Nogueira Renata Campos, Taslimi Jaafar, Ali Hayder, Najem Mohammed, Shukur Mahmood Mustafa, Abdullah Khaleel Ibrahim, Saad Mohammed Abdulqader, Ramadhan Hasan Hasan, Marcourt Laurence, Félix Fabien, Vinh Tri Low-Der's Nicolas, Ferreira Queiroz Emerson, Wolfender Jean-Luc, Watissée Marie, Graz Bertrand
Antenna Foundation, Avenue de la Grenade 24, 1207 Geneva, Switzerland.
The Iraq Health Access Organization ("IHAO"), District 901, Abu Nawas ST, Baghdad, Iraq.
Plants (Basel). 2021 May 19;10(5):1018. doi: 10.3390/plants10051018.
In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using () decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group ( = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group ( = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP's problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product.
2019年，伊拉克约有140万国内流离失所者；医疗救治常常中断。对使用（）汤剂控制高血压的可行性进行了评估。对121名高血压（BP）（≥140/90 mmHg）患者开展了一项多中心比较性试点干预。干预组参与者（无论是否使用常规药物）按照从每天10克开始的剂量方案服用汤剂。在六周内测量了五次血压。对主要活性物质进行了化学定量分析。结果：六周后，干预组61.8%的参与者（ = 76）血压达到<140/90 mmHg的目标，而对照组这一比例为6.7%（ = 45）。在干预组，收缩压和舒张压平均（±标准差）分别降低了23.1（±11.8）mmHg和12.0（±11.2）mmHg，而对照组的降低幅度为4.4（±10.2）/3.6（±8.7）。起始剂量的化学分析表明总花青素含量为36毫克，木槿酸含量为2.13克。该研究表明，在国内流离失所者的问题背景下使用木槿汤剂是可行的，因为木槿是一种安全、本地可得、价格低廉且在文化上可接受的食品。
