黑腹果蝇在超重力环境下的应激抗性与年龄的关系。

Resistance to stress as a function of age in Drosophila melanogaster living in hypergravity.

作者信息

Minois N, Le Bourg E

机构信息

Department of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul 55108, USA.

出版信息

Mech Ageing Dev. 1999 Jun 1;109(1):53-64. doi: 10.1016/s0047-6374(99)00025-1.

DOI:10.1016/s0047-6374(99)00025-1

PMID:10405989

Abstract

Male and female fruitflies (Drosophila melanogaster) living at different gravity levels [1g: terrestrial gravity; 3 and 5g: hypergravity (HG)] were used to investigate the age-specific (young: 7 days; middle-aged: 28 days; and old: 49 days) resistance to various stresses (starvation, desiccation, and cold). The experiment showed that the resistance of the flies to the studied stresses decreased with age, except in the case of females submitted to starvation which was increased. These variations were explained by the amount of lipid. Variation in desiccation resistance was not explained by the amount of water. As a function of gravity, no or slight differences were observed for the studied stresses. The resistance to heat of young flies increased with the gravity level. This resistance was not explained by a decreased locomotor activity of HG-living flies during heat stress, nor by the water and lipid contents.

摘要

利用生活在不同重力水平下的雄性和雌性果蝇（黑腹果蝇）[1g：地球重力；3g和5g：超重力（HG）]来研究不同年龄阶段（年轻：7天；中年：28天；老年：49天）对各种应激（饥饿、干燥和寒冷）的抵抗力。实验表明，果蝇对所研究应激的抵抗力随年龄增长而下降，但遭受饥饿的雌性果蝇除外，其抵抗力有所增加。这些变化是由脂质含量来解释的。干燥抗性的变化并非由水量来解释。就重力而言，在所研究的应激方面未观察到差异或仅有轻微差异。年轻果蝇的耐热性随重力水平的增加而提高。这种抗性既不能通过生活在超重力环境下的果蝇在热应激期间运动活性的降低来解释，也不能通过水和脂质含量来解释。