Pongstaporn W, Bunyaratavej A
Department of Clinical Microscopy, Faculty of Medical Technology, Rangsit University, Pathumthani, Thailand.
J Med Assoc Thai. 1999 Mar;82(3):304-11.
Hematological parameters and serum ferritin were compared between 179 vegetarians and 58 control subjects using Hematology analyzer H3 and microparticle enzyme immunoassay, respectively. Serum Vitamin B12 was also compared between 68 vegetarians and 30 control subjects using microparticle enzyme immunoassay. It was found that hemoglobin, hematocrit, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, white blood cells, neutrophils, serum ferritin and serum vitamin B12 in vegetarian were significantly lower than control subjects (P < 0.05). In addition, red cell distribution width and lymphocytes in vegetarians were significantly higher than control subjects (P < 0.05). There were 34 cases of iron deficiency in 179 vegetarians (19.%) which can be classified to iron depletion (4 cases), iron deficient erythropoiesis (12 cases) and iron deficiency anemia (18 cases). Vitamin B12 deficiency was found in 27 cases of 68 vegetarians (40%).
分别使用血液分析仪H3和微粒酶免疫分析法,对179名素食者和58名对照者的血液学参数和血清铁蛋白进行了比较。还使用微粒酶免疫分析法,对68名素食者和30名对照者的血清维生素B12进行了比较。结果发现,素食者的血红蛋白、血细胞比容、平均红细胞血红蛋白、平均红细胞血红蛋白浓度、白细胞、中性粒细胞、血清铁蛋白和血清维生素B12显著低于对照者(P < 0.05)。此外,素食者的红细胞分布宽度和淋巴细胞显著高于对照者(P < 0.05)。179名素食者中有34例缺铁(19.%),可分为铁耗竭(4例)、缺铁性红细胞生成(12例)和缺铁性贫血(18例)。68名素食者中有27例(40%)发现维生素B12缺乏。