Celada A, Busset R, Gutierrez J, Herreros V
Int J Biol Res Pregnancy. 1981;2(3):142-5.
The levels of serum ferritin, folates, and vitamin B12 in relation to the hematologic values were measured in 66 pregnant women at term who had been supplemented with iron (100 mg/day) and folate (350 microgram/day). The levels of hemoglobin in pregnant women were similar to the controls;' however, levels of ferritin and transferrin saturation were decreased and showed a correlation with the hemoglobin. The MCV increased, whereas folate and vitamin B12 decreased, but no correlation was found between these values. These results suggest that in pregnant women (a) serum ferritin and transferrin saturation reflect the iron available for erythropoiesis, (b) the iron supplementation of 100 mg/day in the population studied is not sufficient, and (c) the macrocytosis is independent of the folate and vitamin B12 levels.
对66名足月孕妇进行了血清铁蛋白、叶酸和维生素B12水平与血液学指标关系的测定，这些孕妇已补充铁剂（100毫克/天）和叶酸（350微克/天）。孕妇的血红蛋白水平与对照组相似；然而，铁蛋白和转铁蛋白饱和度水平降低，且与血红蛋白呈相关性。平均红细胞体积增加，而叶酸和维生素B12水平降低，但这些值之间未发现相关性。这些结果表明，对于孕妇，（a）血清铁蛋白和转铁蛋白饱和度反映了可用于红细胞生成的铁，（b）在所研究人群中每天补充100毫克铁是不够的，（c）大细胞性贫血与叶酸和维生素B12水平无关。
