Tungtrongchitr R, Pongpaew P, Prayurahong B, Changbumrung S, Vudhivai N, Migasena P, Schelp F P
Department of Tropical Nutrition and Food Science, Faculty of Tropical Medicine, Mahidol University.
Int J Vitam Nutr Res. 1993;63(3):201-7.
Serum vitamin B12, folic acid and haematological variables of 132 Thai vegetarians (64 males and 68 females) were investigated. Forty-seven healthy omnivorous individuals served as controls. No statistical differences in haemoglobin concentration, packed red cell volume and mean corpuscular haemoglobin concentration between the vegetarians and controls had been detected. In the female vegetarians, the haemoglobin concentration and packed red cell volume were, however, statistically lower. No significant differences in the white cell counts and platelet counts were observed in both groups. A significant increase of basophilic stippling and reticulocytes was observed in the vegetarians. Serum vitamin B12 decreased and serum folic acid levels increased according to the duration of vegetarianism in the vegetarians. In the females practicing vegetarianism for 6-10 years or more, the proportion of serum vitamin B12 deficiencies was particularly high. The high percentage of vitamin B12 deficiency in the vegetarians might be related to megaloblastic anaemia. This form of anaemia is commonly associated with the presence of basophilic stippling. Therefore, the increased presence of basophilic stippling and reticulocytes might indicate a mild stage of this type of anaemia among the vegetarians.
对132名泰国素食者（64名男性和68名女性）的血清维生素B12、叶酸和血液学指标进行了调查。47名健康的杂食者作为对照。未检测到素食者和对照组之间血红蛋白浓度、红细胞压积和平均红细胞血红蛋白浓度有统计学差异。然而，女性素食者的血红蛋白浓度和红细胞压积在统计学上较低。两组的白细胞计数和血小板计数均未观察到显著差异。素食者中嗜碱性点彩红细胞和网织红细胞显著增加。素食者血清维生素B12水平降低，血清叶酸水平根据素食时间增加。在素食6至10年或更长时间的女性中，血清维生素B12缺乏的比例特别高。素食者中维生素B12缺乏的高比例可能与巨幼细胞贫血有关。这种贫血形式通常与嗜碱性点彩红细胞的存在有关。因此，嗜碱性点彩红细胞和网织红细胞数量的增加可能表明素食者中这种贫血处于轻度阶段。
