Pierallini A, Piattella M C, Polli N S, Bonamini M, Angeloni U, David V, Bozzao L
Dipartimento di Scienze Neurologiche, Università La Sapienza, Roma.
Radiol Med. 1999 Apr;97(4):236-40.
To evaluate the yield of SPIR sequences with fat suppression in the diagnosis of optic nerve lesions.
Ten patients with suspected optic nerve involvement on the basis of clinical data and abnormalities of visual evoked potentials were examined. MRI was performed with a 1.5 T unit (Philips NT 15) using T1 weighted conventional spin-echo and T1- and T2 weighted SPIR sequences with fat suppression. Axial images were obtained along the optic nerve course, while coronal images throughout the optic nerve axis; slices were 3 mm thick. Axial T2 weighted SPIR sequences were also performed with the volumetric technique (1.5 mm thickness); coronal and parasagittal reconstructions along the nerve axis were obtained too. After paramagnetic contrast medium injection, conventional T1 weighted and SPIR sequences were performed on axial and coronal planes.
Optic nerve lesions consistent with the diagnosis of neuritis were demonstrated with T2 weighted images in 4 of 10 patients. No abnormalities and/or nerve enlargement were found on T1 weighted images. An enhancement area was seen after contrast medium injection in only one case. MRI showed a pilocytic astrocytoma in one patient and selective atrophy of the right optic nerve in another. MRI showed normal findings in 4 patients.
T1 and T2 weighted fat-suppressed SPIR imaging of the optic nerve improves anatomical definition, lesion detection and characterization in optic nerve conditions.
评估脂肪抑制的SPIR序列在视神经病变诊断中的检出率。
对10例根据临床资料及视觉诱发电位异常怀疑视神经受累的患者进行检查。使用1.5T设备（飞利浦NT 15）进行MRI检查，采用T1加权常规自旋回波序列以及T1加权和T2加权脂肪抑制SPIR序列。沿视神经走行获取轴位图像，贯穿视神经轴获取冠状位图像；层厚3mm。还采用容积技术（层厚1.5mm）进行轴位T2加权SPIR序列检查，并沿神经轴进行冠状位和矢状旁位重建。注射顺磁性造影剂后，在轴位和冠状位平面进行常规T1加权和SPIR序列检查。
10例患者中有4例在T2加权图像上显示符合神经炎诊断的视神经病变。T1加权图像上未发现异常和/或神经增粗。仅1例在注射造影剂后可见强化区域。MRI显示1例患者为毛细胞型星形细胞瘤，另1例患者右侧视神经选择性萎缩。4例患者MRI表现正常。
视神经的T1加权和T2加权脂肪抑制SPIR成像可改善视神经疾病的解剖结构显示、病变检测及特征描述。
