Bhopal R, Unwin N, White M, Yallop J, Walker L, Alberti K G, Harland J, Patel S, Ahmad N, Turner C, Watson B, Kaur D, Kulkarni A, Laker M, Tavridou A
Department of Epidemiology and Public Health, Medical School, University of Newcastle, Newcastle upon Tyne NE2 4HH.
BMJ. 1999 Jul 24;319(7204):215-20. doi: 10.1136/bmj.319.7204.215.
To compare coronary risk factors and disease prevalence among Indians, Pakistanis, and Bangladeshis, and in all South Asians (these three groups together) with Europeans.
Cross sectional survey.
Newcastle upon Tyne.
259 Indian, 305 Pakistani, 120 Bangladeshi, and 825 European men and women aged 25-74 years.
Social and economic circumstances, lifestyle, self reported symptoms and diseases, blood pressure, electrocardiogram, and anthropometric, haematological, and biochemical measurements.
There were differences in social and economic circumstances, lifestyles, anthropometric measures and disease both between Indians, Pakistanis, and Bangladeshis and between all South Asians and Europeans. Bangladeshis and Pakistanis were the poorest groups. For most risk factors, the Bangladeshis (particularly men) fared the worst: smoking was most common (57%) in that group, and Bangladeshis had the highest concentrations of triglycerides (2.04 mmol/l) and fasting blood glucose (6.6 mmol/l) and the lowest concentration of high density lipoprotein cholesterol (0.97 mmol/l). Blood pressure, however, was lowest in Bangladeshis. Bangladeshis were the shortest (men 164 cm tall v 170 cm for Indians and 174 cm for Europeans). A higher proportion of Pakistani and Bangladeshi men had diabetes (22.4% and 26.6% respectively) than Indians (15.2%). Comparisons of all South Asians with Europeans hid some important differences, but South Asians were still disadvantaged in a wide range of risk factors. Findings in women were similar.
Risk of coronary heart disease is not uniform among South Asians, and there are important differences between Indians, Pakistanis, and Bangladeshis for many coronary risk factors. The belief that, except for insulin resistance, South Asians have lower levels of coronary risk factors than Europeans is incorrect, and may have arisen from combining ethnic subgroups and examining a narrow range of factors.
比较印度人、巴基斯坦人和孟加拉国人以及所有南亚人（这三个群体合称）与欧洲人之间的冠心病危险因素及疾病患病率。
横断面调查。
泰恩河畔纽卡斯尔。
259名年龄在25 - 74岁之间的印度男性和女性、305名巴基斯坦男性和女性、120名孟加拉国男性和女性以及825名欧洲男性和女性。
社会经济状况、生活方式、自我报告的症状和疾病、血压、心电图以及人体测量学、血液学和生物化学测量指标。
印度人、巴基斯坦人和孟加拉国人之间以及所有南亚人和欧洲人之间在社会经济状况、生活方式、人体测量指标和疾病方面存在差异。孟加拉国人和巴基斯坦人是最贫困的群体。对于大多数危险因素，孟加拉国人（尤其是男性）情况最差：该群体吸烟最为普遍（57%），孟加拉国人的甘油三酯浓度最高（2.04毫摩尔/升）、空腹血糖最高（6.6毫摩尔/升），高密度脂蛋白胆固醇浓度最低（0.97毫摩尔/升）。然而，孟加拉国人的血压最低。孟加拉国人最矮（男性身高164厘米，印度男性为170厘米，欧洲男性为174厘米）。患有糖尿病的巴基斯坦和孟加拉国男性比例（分别为22.4%和26.6%）高于印度男性（(15.2%）。所有南亚人与欧洲人的比较掩盖了一些重要差异，但南亚人在众多危险因素方面仍处于劣势。女性的研究结果相似。
南亚人患冠心病的风险并不一致，印度人、巴基斯坦人和孟加拉国人在许多冠心病危险因素方面存在重要差异。认为除胰岛素抵抗外，南亚人冠心病危险因素水平低于欧洲人的观点是错误的，这可能是由于将不同种族亚组合并并仅考察了有限范围的因素所致。
