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浅表异物损伤后角膜伤口愈合:维生素A、泛醇与小牛血提取物的对比。一项随机双盲研究。

Corneal wound healing after superficial foreign body injury: vitamin A and dexpanthenol versus a calf blood extract. A randomized double-blind study.

作者信息

Egger S F, Huber-Spitzy V, Alzner E, Scholda C, Vecsei V P

机构信息

County Hospital of Salzburg, Austria.

出版信息

Ophthalmologica. 1999;213(4):246-9. doi: 10.1159/000027429.

DOI:10.1159/000027429
PMID:10420108
Abstract

A prospective randomized double-blind clinical study was performed to investigate corneal wound healing after treatment either with an eye gel containing calf blood extract or an eye ointment containing vitamin A and dexpanthenol. A total of 54 outpatients were included in this study, all treated for corneal foreign body injury. The size of the corneal lesions was measured by planimetry on days 0, 1, and on the following days until complete epithelial healing occurred. Results showed the calf blood extract eye gel to be statistically more effective in promoting corneal wound healing, especially in patients with wound areas larger than 6 mm(2).

摘要

进行了一项前瞻性随机双盲临床研究,以调查用含小牛血提取物的眼凝胶或含维生素A和泛醇的眼膏治疗后角膜伤口的愈合情况。本研究共纳入54名门诊患者,均因角膜异物损伤接受治疗。在第0天、第1天以及之后直至角膜上皮完全愈合的每一天,通过平面测量法测量角膜病变的大小。结果显示,含小牛血提取物的眼凝胶在促进角膜伤口愈合方面具有统计学意义上的更显著效果,尤其是对于伤口面积大于6平方毫米的患者。

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