夹竹桃根中的类固醇。

Steroids from the roots of Nerium oleander.

作者信息

Huq M M, Jabbar A, Rashid M A, Hasan C M, Ito C, Furukawa H

机构信息

Phytochemical Research Laboratory, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.

出版信息

J Nat Prod. 1999 Jul;62(7):1065-7. doi: 10.1021/np990031b.

DOI:10.1021/np990031b

PMID:10425146

Abstract

Two new cardenolides, 3beta-hydroxy-5alpha-carda-14(15), 20(22)-dienolide (beta-anhydroepidigitoxigenin) (1) and 3beta-O-(D-digitalosyl)-21-hydroxy-5beta-carda-8,14,16 , 20(22)-tetraenolide (neriumogenin-A-3beta-D-digitaloside) (2), and two known compounds, proceragenin and neridienone A (3), have been isolated from the roots of Nerium oleander. The structures of 1 and 2 were elucidated on the basis of spectral data interpretation.

摘要

从夹竹桃的根中分离出了两种新的强心苷，3β-羟基-5α-卡丹-14(15),20(22)-二烯醇内酯（β-脱水表地高辛配基）(1)和3β-O-(D-洋地黄糖基)-21-羟基-5β-卡丹-8,14,16,20(22)-四烯醇内酯（夹竹桃苷元-A-3β-D-洋地黄糖苷）(2)，以及两种已知化合物，前夹竹桃苷元和夹竹桃二烯酮A(3)。根据光谱数据解析确定了1和2的结构。