Chen Huan, Xu Nan, Zhou Yuzhi, Qiao Li, Cao Jiaqing, Yao Yao, Hua Huiming, Pei Yuehu
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenyang 110016, People's Republic of China.
Steroids. 2008 Jul;73(6):629-36. doi: 10.1016/j.steroids.2008.01.024. Epub 2008 Feb 9.
Seven new steroidal glycosides (amplexicosides A (4), B (7), C (8), D (9), E (10), F (11), and G (12)), along with six known compounds (cynatratoside A (1), tylophoside A (2), cynatratoside B (3), glaucogenin A (5), glaucoside A (6), and hancoside A (13)) were isolated from the 95% ethanol extract of the roots of Cynanchum amplexicaule (Sieb. et Zucc.). Their structures were determined based on spectral and chemical evidence. Compound 12 has a 14, 15-secopregnane-type skeleton aglycone, which has not been reported in literature.
从白薇（Cynanchum amplexicaule (Sieb. et Zucc.)）根的95%乙醇提取物中分离得到7个新的甾体糖苷（环抱苷A（4）、B（7）、C（8）、D（9）、E（10）、F（11）和G（12））以及6个已知化合物（杯冠苷A（1）、娃儿藤苷A（2）、杯冠苷B（3）、青阳参苷元A（5）、青阳参苷A（6）和汉柯苷A（13））。基于光谱和化学证据确定了它们的结构。化合物12具有14,15-断孕甾烷型骨架苷元，该结构尚未见文献报道。
