Henson D A, Nieman D C, Blodgett A D, Butterworth D E, Utter A, Davis J M, Sonnenfeld G, Morton D S, Fagoaga O R, Nehlsen-Cannarella S L
Department of Biology, Appalachian State University, Boone, NC 28608, USA.
Int J Sport Nutr. 1999 Jun;9(2):213-28. doi: 10.1123/ijsn.9.2.213.
The influence of exercise mode and 6% carbohydrate (C) versus placebo (P) beverage ingestion on lymphocyte proliferation, natural killer cell cytotoxicity (NKCA), Interleukin (IL)-1beta production, and hormonal responses to 2.5 hr of intense running and cycling (approximately 75% VO2max) was measured in 10 triathletes serving as their own controls. The C versus P condition (but not exercise mode) resulted in higher plasma glucose concentrations, lower plasma cortisol concentrations, reduced postexercise lymphocytosis and NKCA, and a lessened T-cell reduction during recovery, No condition or mode effects were observed for concanavalin A and phytohemagglutinin-induced lymphocyte proliferation. Significant mode (but not condition) effects were observed for lipopolysaccharide-induced IL-1beta production over time. However, when expressed per monocyte, the mode effect was abolished and a sustained suppression in IL-1beta/monocyte was observed in all sessions throughout recovery. These data indicate that carbohydrate ingestion significantly affects plasma glucose and cortisol concentrations, blood lymphocyte counts, and NKCA, whereas exercise mode has no effect on these parameters.
以10名铁人三项运动员作为自身对照，测量了运动模式以及摄入6%碳水化合物（C）饮料与安慰剂（P）饮料对淋巴细胞增殖、自然杀伤细胞细胞毒性（NKCA）、白细胞介素（IL）-1β产生以及对2.5小时高强度跑步和骑行（约75%最大摄氧量）的激素反应的影响。C组与P组对比（但不是运动模式）导致血浆葡萄糖浓度升高、血浆皮质醇浓度降低、运动后淋巴细胞增多症和NKCA减少，以及恢复期间T细胞减少减轻。对于伴刀豆球蛋白A和植物血凝素诱导的淋巴细胞增殖，未观察到条件或模式效应。随着时间推移，在脂多糖诱导的IL-1β产生方面观察到显著的模式（而非条件）效应。然而，以每个单核细胞表示时，模式效应消失，并且在整个恢复过程的所有时段中均观察到IL-1β/单核细胞持续受到抑制。这些数据表明，摄入碳水化合物会显著影响血浆葡萄糖和皮质醇浓度、血液淋巴细胞计数以及NKCA，而运动模式对这些参数没有影响。
