Laccourreye O, Hans S, Ménard M, Hacquart N, Brasnu D, Crevier-Buchman L
Service d'oto-rhino-laryngologie et de chirurgie cervicofaciale, Assistance publique des hôpitaux de Paris, Université Paris V, France.
Chirurgie. 1999 Jun;124(3):283-7. doi: 10.1016/s0001-4001(99)80094-4.
An analysis of the results achieved with intracordal autologous fat injection for unilateral laryngeal nerve paralysis after surgery.
A study group of 46 patients with unilateral laryngeal nerve paralysis was treated by intracordal injection of autologous fat with a minimum follow-up of eight months. All patients had severe dysphonia and 39 had breathlessness. Twenty-nine patients had aspiration problems with difficulties in swallowing.
The only adverse side-effect was a subcutaneous abdominal hematoma in two patients and the development of an intracordal cyst in two patients. Aspiration disappeared immediately after the intracordal injection. Immediate improvement of speech, cough, and breathlessness was achieved in all patients. Over time, speech and voice, and swallowing remained stable in 67% and 80% of patients, respectively.
Such data suggest that the intracordal injection of autologous fat is a valuable method in patients with unilateral laryngeal nerve paralysis after surgery.
分析手术后单侧喉返神经麻痹采用声带内自体脂肪注射所取得的结果。
46例单侧喉返神经麻痹患者组成的研究组接受声带内自体脂肪注射治疗，最短随访8个月。所有患者均有严重发音障碍，39例伴有气促。29例有吞咽困难伴误吸问题。
仅2例出现腹部皮下血肿，2例出现声带内囊肿等不良反应。声带内注射后误吸立即消失。所有患者的言语、咳嗽和气促症状立即得到改善。随着时间推移，分别有67%和80%的患者言语、嗓音及吞咽功能保持稳定。
这些数据表明，声带内注射自体脂肪对于手术后单侧喉返神经麻痹患者是一种有价值的方法。
