Michel F, Hans S, Crevier-Buchman L, Brasnu D, Menard M, Laccourreye O
Service d'oto-rhino-laryngologie et de chirurgie cervico-faciale, hôpital européen Georges Pompidou, assistance publique des hôpitaux de Paris, université Paris V, 20-40 rue Leblanc, 75015, Paris.
Ann Otolaryngol Chir Cervicofac. 2003 Nov;120(5):259-67.
Based on an inception cohort of 63 patients with unilateral vocal fold paralysis consecutively treated with thyroplasty and Montgomery's implant under local anesthesia during the years 1997-2002, we recorded i) morbidity and mortality, ii) evolution of dysphonia and swallowing impairment and iii) a prospective analysis of selected speech and voice parameters in an attempt to determine their evolution during the first 12 postoperative months and to search for potential statistical relationships with the following variables (age, gender, side of the paralysis, etiology of the paralysis, time between onset of paralysis and thyroplasty, position of the paralyzed true vocal fold, nerve involved, associated pneumonectomy, prior intracordal injection of autologous fat and surgeon).
The overall complication rate was 8%. Minor complications occurred in 6.5% of the patients and included 4 cases of laryngeal edema successfully treated with oral steroids. Major complications occurred in 1.5% of the patients. Intralaryngeal hematoma requiring temporary tracheotomy was the major complication. Swallowing was improved in 93.5% of the patients. Immediate improvement of speech and voice was noted in all. Secondary degradation of speech and voice occurred in one patient. At revision thyroplasty lateral displacement of the implant was noted and successfully repositioned. At one month post-operatively, the values of maximum phonation time, speech rate, group phrasing standard deviation of the fundamental frequency, jitter and shimmer were statistically improved while the fundamental frequency did not vary significantly. At 12 months post-operatively the noise to harmonic ratio was improved while the other parameters remained stable. No significant statistical relationship was found between the post-operative speech and voice parameters and the variables under analysis.
Based on the current series and a review of the medical literature, thyroplasty with Montgomery's implant under local anesthesia appears to be an easy, effective and safe procedure that might be used in all patients with unilateral laryngeal nerve paralysis.
基于1997年至2002年间63例单侧声带麻痹患者的初始队列,这些患者均在局部麻醉下接受了甲状成形术和蒙哥马利植入物治疗,我们记录了:i)发病率和死亡率;ii)发音障碍和吞咽障碍的演变;iii)对选定的言语和嗓音参数进行前瞻性分析,以确定其在术后12个月内的演变情况,并寻找与以下变量(年龄、性别、麻痹侧、麻痹病因、麻痹发作与甲状成形术之间的时间、麻痹的真声带位置、受累神经、相关肺切除术、先前的自体脂肪声带内注射以及外科医生)之间的潜在统计关系。
总体并发症发生率为8%。6.5%的患者出现轻微并发症,包括4例经口服类固醇成功治疗的喉水肿。1.5%的患者出现严重并发症。需要临时气管切开术的喉内血肿是主要并发症。93.5%的患者吞咽功能得到改善。所有患者的言语和嗓音均立即得到改善。1例患者出现言语和嗓音的继发性退化。在翻修甲状成形术时,发现植入物侧向移位并成功重新定位。术后1个月,最大发声时间、语速、基频的组内短语标准差、抖动和闪烁值在统计学上有所改善,而基频无显著变化。术后12个月,噪声谐波比得到改善,而其他参数保持稳定。未发现术后言语和嗓音参数与所分析变量之间存在显著的统计关系。
基于当前系列研究以及对医学文献的回顾,局部麻醉下使用蒙哥马利植入物进行甲状成形术似乎是一种简单、有效且安全的手术方法,可用于所有单侧喉返神经麻痹患者。