库鲁病、克雅氏病和羊瘙痒病病毒对电离辐射具有异常抗性。
Unusual resistance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie.
作者信息
Gibbs C J, Gajdusek D C, Latarjet R
出版信息
Proc Natl Acad Sci U S A. 1978 Dec;75(12):6268-70. doi: 10.1073/pnas.75.12.6268.
Abstract
The titers of several preparations of kuru. Creutzfeldt-Jacob disease, and scrapie viruses were reduced by only 1/10th or less by high doses of gamma radiation of 50 kGy and by only 1/10th-1/1000th or less for 200 kGy. This unusual radiation resistance of the two human viruses further links them with the scrapie virus and suggests that the genetic information of all three viruses is considerably smaller than that of any other known viruses of mammals.
摘要
几种库鲁病、克雅氏病和羊瘙痒病病毒制剂的滴度，在50千戈瑞的高剂量伽马辐射下仅降低了十分之一或更少，而在200千戈瑞时仅降低了十分之一至千分之一或更少。这两种人类病毒这种不同寻常的辐射抗性进一步将它们与羊瘙痒病病毒联系起来，并表明这三种病毒的遗传信息比任何其他已知的哺乳动物病毒都要小得多。
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