Hendricks M V, Crosby J H, Davis W B
Section of Pulmonary Diseases, Department of Medicine, and Department of Pathology, Medical College of Georgia, Augusta, Georgia, USA.
Am J Respir Crit Care Med. 1999 Aug;160(2):730-1. doi: 10.1164/ajrccm.160.2.9812159.
A case of pulmonary sarcoidosis is presented in which cytologic analysis of bronchoalveolar (BAL) fluid showed intact granulomas. The patient had severe alveolar inflammation and probable endobronchial sarcoidosis. Thus the granulomas in the BAL fluid probably reflect a high burden of alveolar wall granulomas and/or the removal of granulomas from proximal inflamed airways. This is the first reported case of granulomas in BAL fluid in sarcoidosis. Although an unusual finding, the recovery of BAL granulomas is not diagnostic for sarcoidosis and cannot substitute for the demonstration of granulomatous inflammation in lung tissue.
本文报告一例肺结节病，其支气管肺泡灌洗（BAL）液的细胞学分析显示肉芽肿完整。患者有严重的肺泡炎症及可能的支气管内结节病。因此，BAL液中的肉芽肿可能反映了肺泡壁肉芽肿的高负荷及/或从近端炎症气道清除的肉芽肿。这是首例报告的结节病患者BAL液中出现肉芽肿的病例。尽管这一发现不常见，但BAL肉芽肿的检出对结节病并无诊断意义，也不能替代肺组织中肉芽肿性炎症的证实。
