Ooshima M, Takahasi T, Matsumoto H, Sasaki N, Sato K, Takeda A, Ogasa T, Hujita Y, Tobise K
National Douhoku Hospital, Hokkaido, Japan.
Nihon Kokyuki Gakkai Zasshi. 1999 Jun;37(6):509-13.
A 23-year-old man complaining of right-sided chest pain was admitted to our hospital for further examination of an abnormal shadow on chest X-ray films. Initially, we suspected the abnormal shadow was that of a pleural effusion in the right thorax. Computed tomographic scans disclosed a tumor in the anterior mediastinum, adjacent to the abnormal shadow. After closer examination, particularly by fluoroscopy on catheterization, we recognized that the abnormal shadow was a giant cyst, and that it connected with a solid mass. There were no abnormal laboratory data on admission. An examination of fluid specimens from the giant cyst revealed high levels of the tumor markers SCC antigen, CEA, and CA 19-9. These findings together suggested that the solid mass with giant cyst might be a mediastinal teratoma. The tumor was completely resectable without serious complications. The giant cyst contained 1,200 ml of fluid, and occupied half the volume of the right thoracic cavity. Pathological examination disclosed that the resected mediastinal tumor was a matured teratoma. Although matured teratoma are often composed of cysts, those that radiologically resemble pleural effusion, as in this case, were considered uncommon.
一名23岁男性因右侧胸痛入院,接受胸部X光片异常阴影的进一步检查。最初,我们怀疑异常阴影是右侧胸腔的胸腔积液。计算机断层扫描显示前纵隔有一个肿瘤,与异常阴影相邻。经过仔细检查,特别是在导管插入术时进行透视检查后,我们认识到异常阴影是一个巨大囊肿,并且它与一个实性肿块相连。入院时实验室检查数据无异常。对巨大囊肿的液体标本进行检查发现肿瘤标志物鳞状细胞癌抗原(SCC抗原)、癌胚抗原(CEA)和糖类抗原19-9(CA 19-9)水平升高。这些发现共同提示伴有巨大囊肿的实性肿块可能是纵隔畸胎瘤。该肿瘤可完全切除,无严重并发症。巨大囊肿含有1200毫升液体,占据右侧胸腔体积的一半。病理检查显示切除的纵隔肿瘤是成熟畸胎瘤。虽然成熟畸胎瘤通常由囊肿组成,但像本例这样在放射学上类似胸腔积液的情况被认为并不常见。