Mezei G
I. Gyermekklinika, Semmelweis Orvostudományi Egyetem, Budapest.
Orv Hetil. 1999 Jul 4;140(27):1519-27.
The primary goals of asthma treatment are to minimize symptoms and preventing exacerbations, and decrease the morbidity of asthma. To improve asthma management international guidelines have been introduced which recommend use prophylactic therapy. Current therapeutic strategies for treating asthma focus on suppressing the inflammatory process by using kromones in mild childhood asthma or inhaled steroids in moderate to severe asthma. The beneficial effects of inhaled corticosteroid outweigh their possible impairing effects on linear body growth. The inhaled route of administration of the drugs is the most appropriate way to treat asthma, it means best clinical effect with the smallest systemic side effect. The age of the child is a major determinant of the inhaled therapy which can be used. Drug delivery in infants and toddlers is the most difficult part of asthma treatment.
哮喘治疗的主要目标是尽量减轻症状、预防病情加重，并降低哮喘的发病率。为改善哮喘管理，已出台国际指南，推荐采用预防性治疗。目前治疗哮喘的策略侧重于通过在轻度儿童哮喘中使用色酮类药物或在中度至重度哮喘中使用吸入性类固醇来抑制炎症过程。吸入性糖皮质激素的有益作用超过其对身体线性生长可能产生的不良影响。药物的吸入给药途径是治疗哮喘的最合适方式，这意味着能以最小的全身副作用获得最佳临床效果。儿童的年龄是可采用的吸入治疗的主要决定因素。婴幼儿的药物递送是哮喘治疗中最困难的部分。
