Feng Y, Li W, Liu Y
Department of Ophthalmology, Peking Union Medical College Hospital, Beijing.
Zhonghua Yan Ke Za Zhi. 1997 Mar;33(2):113-6.
To study the characteristics of macular light sensitivity (MLS) and relative afferent pupillary defect (RAPD) in anisometropic and ametropic amblyopia in school-aged children.
By using the static perimetry technique and swinging light test, we assessed MLS and RAPD in normal subjects, anisometropic and ametropic amblyopia in school-aged children.
In comparison with the normal group, the MLS in both anisometropic and ametropic amblyopic eyes was significantly depressed. The MLS of the fellow eyes of the amblyopic eyes in anisometropic subjects was also depressed as compared with that of the normal group. The rate of RAPD was positive in 34.29% in the anisometropic amblyopic group.
The static perimetry technique demonstrates a marked depression of MLS in all amblyopic eyes tested, suggesting a defect of visual X-channel. The pathogenesis of monocular amblyopia and binocular amblyopia is probably different, thus MLS examination can help assess prognosis. RAPD in anisometropic amblyopia may reflect a deficiency of peripheral visual system. The fellow eye of the anisometropic amblyopia eye may also be abnormal in terms of psychophysical standard.
研究学龄期儿童屈光参差性弱视和屈光不正性弱视的黄斑光敏感度（MLS）及相对传入性瞳孔障碍（RAPD）的特征。
采用静态视野检查技术和摆灯试验，对正常受试者、学龄期儿童屈光参差性弱视和屈光不正性弱视进行MLS和RAPD评估。
与正常组相比，屈光参差性弱视眼和屈光不正性弱视眼的MLS均显著降低。屈光参差性弱视患者弱视眼的对侧眼的MLS与正常组相比也降低。屈光参差性弱视组中RAPD阳性率为34.29%。
静态视野检查技术显示，所有受检弱视眼的MLS均显著降低，提示存在视觉X通道缺陷。单眼弱视和双眼弱视的发病机制可能不同，因此MLS检查有助于评估预后。屈光参差性弱视中的RAPD可能反映了外周视觉系统的缺陷。从心理物理学标准来看，屈光参差性弱视眼的对侧眼也可能异常。
