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卡他莫拉菌（布兰汉菌属）BROβ-内酰胺酶：一种源于革兰氏阳性菌的脂蛋白？

Moraxella (Branhamella) catarrhalis BRO beta-lactamase: a lipoprotein of gram-positive origin?

作者信息

Bootsma H J, Aerts P C, Posthuma G, Harmsen T, Verhoef J, van Dijk H, Mooi F R

机构信息

Eijkman-Winkler Institute for Microbiology, Infectious Diseases, and Inflammation, University Hospital Utrecht, Utrecht, The Netherlands.

出版信息

J Bacteriol. 1999 Aug;181(16):5090-3. doi: 10.1128/JB.181.16.5090-5093.1999.

DOI:10.1128/JB.181.16.5090-5093.1999
PMID:10438784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC94001/
Abstract

In the past 20 years, BRO beta-lactamase-producing Moraxella catarrhalis strains have emerged. We show that BRO is expressed as a 33-kDa lipoprotein associated with the inner leaflet of the outer membrane. To our knowledge, this is the first description of a lipidated beta-lactamase in a gram-negative species.

摘要

在过去20年中，已出现产BROβ-内酰胺酶的卡他莫拉菌菌株。我们发现BRO作为一种与外膜内小叶相关的33 kDa脂蛋白表达。据我们所知，这是革兰氏阴性菌中脂化β-内酰胺酶的首次描述。

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