Ye F Q, Yang Y, Duyn J, Mattay V S, Frank J A, Weinberger D R, McLaughlin A C
Clinical Brain Disorders Branch, National Institute of Mental Health, NIH, Bethesda, Maryland 20892, USA.
Magn Reson Med. 1999 Aug;42(2):404-7. doi: 10.1002/(sici)1522-2594(199908)42:2<404::aid-mrm23>3.0.co;2-0.
Steady-state arterial spin tagging approaches were used to construct multislice images of relative cerebral blood flow changes during finger-tapping tasks. Statistically significant increases in cerebral blood flow were observed in primary sensorimotor cortex in all seven subjects. The mean volume of the activated region in the contralateral primary sensorimotor cortex was 0.9 cm(3), and the mean increase in cerebral blood flow in the activated area was 54% +/- 11%. Although the extended spatial coverage is advantageous for activation studies, the intrinsic sensitivity of the multislice approach is smaller than the intrinsic sensitivity of the single-slice, arterial spin tagging approach. Magn Reson Med 42:404-407, 1999. Published 1999 Wiley-Liss, Inc.
采用稳态动脉自旋标记方法构建了手指敲击任务期间相对脑血流变化的多层图像。在所有7名受试者的初级感觉运动皮层中均观察到脑血流有统计学意义的增加。对侧初级感觉运动皮层激活区域的平均体积为0.9立方厘米，激活区域脑血流的平均增加为54%±11%。尽管扩展的空间覆盖范围对激活研究有利，但多层方法的固有灵敏度低于单层面动脉自旋标记方法。《磁共振医学》42:404 - 407, 1999年。1999年由威利 - 利斯公司出版。
