Karpovich E I, Kazakova L V, Kriukova N E, Gustov A V, Lukushkina E F
Zh Nevrol Psikhiatr Im S S Korsakova. 1999;99(7):8-11.
Clinical electroneuromyography (ENMG) was carried out in 63 children aged 2-17 years with polyneuropathy (PNP). Correlations were studied between the results of the laboratory studies and ENMG evidence, duration, severity of diabetes mellitus (DM). Diabetic PNP was characterised as demyelinating motor-sensory or sensory PNP. ENMG signs of axonopathy and of a sensory block of the conductivity through the nerves of lower extremities at early stages of DM were estimated as prognostically unfavourable ones in terms of trophic complications development. Duration of DM had some influence on the nervous conductivity, while axonal function was more stable. The factor that determined the severity of PNP course was the age of DM onset. It resulted in the necessity of more accurate control because of the risk of PNP development in children with DM onset at the age of 12-13 years. At early stages of DM conductivity through peripheral nerves correlated with the level of glycosylated hemoglobin and with the frequency of hypoglycemic states.
对63名2至17岁患有多发性神经病（PNP）的儿童进行了临床神经肌电图检查（ENMG）。研究了实验室检查结果与ENMG证据、糖尿病（DM）病程及严重程度之间的相关性。糖尿病性PNP的特征为脱髓鞘性运动感觉或感觉性PNP。就营养并发症的发生而言，糖尿病早期轴索性病变及下肢神经传导感觉阻滞的ENMG征象被认为预后不良。糖尿病病程对神经传导有一定影响，而轴索功能更稳定。决定PNP病程严重程度的因素是糖尿病发病年龄。由于12至13岁发病的糖尿病儿童有发生PNP的风险，因此有必要进行更精确的控制。在糖尿病早期，外周神经传导与糖化血红蛋白水平及低血糖状态的发生频率相关。
