Saffman E E, Lasko P
Department of Biology, McGill University, Montréal, Québec, Canada.
Cell Mol Life Sci. 1999 Jul;55(8-9):1141-63. doi: 10.1007/s000180050363.
In all animals information is passed from parent to offspring via the germline, which segregates from the soma early in development and undergoes a complex developmental program to give rise to the adult gametes. Many aspects of germline development have been conserved throughout the animal kingdom. Here we review the unique properties of germ cells, the initial determination of germ cell fates, the maintenance of germ cell identity, the migration of germ cells to the somatic gonadal primordia and the proliferation of germ cells during development invertebrates and invertebrates. Similarities in germline development in such diverse organisms as Drosophila melanogaster, Caenorhabditis elegans, Xenopus laevis and Mus musculus will be highlighted.
在所有动物中,信息通过种系从亲代传递给子代,种系在发育早期与体细胞分离,并经历复杂的发育程序以产生成熟配子。种系发育的许多方面在整个动物界都是保守的。在这里,我们综述了生殖细胞的独特特性、生殖细胞命运的初始决定、生殖细胞身份的维持、生殖细胞向体细胞性腺原基的迁移以及生殖细胞在无脊椎动物和脊椎动物发育过程中的增殖。我们将着重介绍果蝇、秀丽隐杆线虫、非洲爪蟾和小家鼠等多种生物在种系发育方面的相似之处。