Hu S, McChesney K A, Player K A, Bahl A M, Buchanan J B, Scozzafava J E
Department of Psychology, Humboldt State University, Arcata, CA 95521, USA.
Aviat Space Environ Med. 1999 Aug;70(8):759-65.
This study investigated the physiological correlates of motion sickness provoked by viewing an optokinetic rotating drum.
A total of 52 subjects viewed an optokinetic rotating drum for 16 min. Subjective symptoms of motion sickness (SSMS) and ratings of over-all sickness were measured during the drum rotation. Electrogastrogram (EGG), electroencephalogram (EEG), electrocardiogram, and skin conductance were measured as physiological correlates of motion sickness.
Analysis by Pearson's correlation showed that the subjects who had higher scores of SSMS during the drum rotation generated the following: a) a higher rating of over-all sickness (r = 0.76); b) a higher ratio of spectral power of EGG at 4-9 cycles per minute (cpm) between drum rotation and baseline periods (r = 0.63); c) a higher net percent increase of spectral power in the EEG frequency band 0.5-4 Hz between drum rotation and baseline periods on C3 (r = 0.29) and C4 (r = 0.31); d) a higher ratio of spectral power of EEG frequency band 0.5-4 Hz between drum rotation and baseline periods on C3 (r = 0.31); and e) a higher level of net increase in skin conductance from baseline to drum rotation (r = 0.30).
The increase of EGG at 4-9 cpm activity, gastric tachyarrhythmia, is the most sensitive physiological index of the severity of symptoms of motion sickness.
本研究调查了观看视动旋转鼓诱发晕动病的生理相关性。
共有52名受试者观看视动旋转鼓16分钟。在鼓旋转期间测量晕动病的主观症状（SSMS）和总体不适评分。测量了胃电图（EGG）、脑电图（EEG）、心电图和皮肤电导率作为晕动病的生理相关性指标。
Pearson相关性分析表明，在鼓旋转期间SSMS得分较高的受试者出现了以下情况：a）总体不适评分较高（r = 0.76）；b）鼓旋转期与基线期之间每分钟4 - 9次循环（cpm）的EGG频谱功率比更高（r = 0.63）；c）鼓旋转期与基线期之间C3（r = 0.29）和C4（r = 0.31）处0.5 - 4 Hz脑电频段频谱功率的净百分比增加更高；d）鼓旋转期与基线期之间C3处0.5 - 4 Hz脑电频段的频谱功率比更高（r = 0.31）；e）从基线到鼓旋转期皮肤电导率的净增加水平更高（r = 0.30）。
4 - 9 cpm活动时EGG增加，即胃性快速心律失常，是晕动病症状严重程度最敏感的生理指标。
