Hartston H J, Swerdlow N R
Joint Doctoral Program in Clinical Psychology, San Diego State University and University of California, USA.
Neuropsychology. 1999 Jul;13(3):447-57. doi: 10.1037//0894-4105.13.3.447.
Two laboratory measures of competitive information processing were studied in obsessive compulsive disorder (OCD) and normal control participants to assess the effects of priming and interfering information on response latency or speed. In the visuospatial priming (VSP) task, key press latency is facilitated or inhibited, depending on the spatial location of a priming cue. In the Stroop task, participants name the ink color of printed words that have an interfering semantic value. OCD participants displayed significantly slowed baseline response latency and increased facilitory priming scores in the VSP task, with no significant difference in VSP inhibition compared with control participants. Higher interference cost in the Stroop task was also observed in OCD participants. Clinical associations between VSP and Stroop performance and specific OCD symptoms were examined. Increased VSP facilitation was most pronounced in OCD participants who reported a history of violent images, tics, "just right" obsessions, or checking compulsions.
在强迫症（OCD）患者和正常对照参与者中，研究了两种竞争性信息处理的实验室测量方法，以评估启动信息和干扰信息对反应潜伏期或速度的影响。在视觉空间启动（VSP）任务中，按键潜伏期会根据启动线索的空间位置而得到促进或抑制。在斯特鲁普任务中，参与者要说出具有干扰语义值的印刷单词的墨水颜色。OCD患者在VSP任务中表现出基线反应潜伏期显著延长，启动促进得分增加，与对照参与者相比，VSP抑制方面无显著差异。在OCD患者中还观察到斯特鲁普任务中的干扰成本更高。研究了VSP和斯特鲁普任务表现与特定OCD症状之间的临床关联。在报告有暴力图像、抽搐、“恰到好处”的强迫观念或检查强迫行为史的OCD患者中，VSP促进增加最为明显。
