Lord R C
Department of Clinical Chemistry, Royal Hallamshire Hospital, Sheffield, UK.
Postgrad Med J. 1999 Feb;75(880):67-73. doi: 10.1136/pgmj.75.880.67.
The maintenance of adequate body fluid volume and the correct distribution of this fluid between the body compartments is a critical part of homeostasis. The process of osmosis plays an important role in movement of fluid within the body and the use of osmometry is an important part of the management of many patients. In addition to the application of osmometry to the measurement of body fluids, most commonly plasma and urine, osmotic action plays a part in some therapeutic actions of drugs and its strength needs to be quantified in fluids administered to patients. Unfortunately confusion often exists in the various terms that are used in the field of osmometry. This review aims to explain the different terms used, the laboratory methodology involved in osmometry, and the clinical application and interpretation of the results obtained.
维持充足的体液量以及该液体在身体各腔室之间的正确分布是体内平衡的关键部分。渗透过程在体内液体的移动中起着重要作用,渗透压测定法的应用是许多患者管理的重要组成部分。除了将渗透压测定法应用于体液(最常见的是血浆和尿液)的测量外,渗透作用在某些药物的治疗作用中也发挥作用,并且需要在给患者使用的液体中对其强度进行量化。不幸的是,渗透压测定领域中使用的各种术语常常存在混淆。本综述旨在解释所使用的不同术语、渗透压测定所涉及的实验室方法以及所获得结果的临床应用和解读。