Spraul C W, Mattfeldt T, Lang G K
Universitäts-Augenklinik Ulm.
Klin Monbl Augenheilkd. 1999 Jul;215(1):68-9. doi: 10.1055/s-2008-1034673.
The most frequent manifestation of an infection with Epstein-Barr virus is the mostly unilateral transient follicular conjunctivitis.
A 19-year-old man was evaluated for a unilateral salmon colored subconjunctival mass that had developed over one week. Additionally, the patient had painful cervical lymph nodes and a sore throat. Blood tests demonstrated a lymphocytosis and a high titer for Epstein-Barr-Virus-IgG and -IgM which was consistent with infectious mononucleosis. A biopsy form the conjunctival mass showed a mixed cellular infiltrate including lymphocytes, plasma cells, histocytes, and cells with a prominent eosinophilic nucleolus. The lesion displayed a spontaneous regression over the following 8 weeks.
Infectious mononucleosis should be considered with a conjunctival tumor which may mimic a lymphoma.
感染爱泼斯坦-巴尔病毒最常见的表现是大多为单侧的短暂性滤泡性结膜炎。
一名19岁男性因单侧鲑鱼色结膜下肿物前来就诊,该肿物在一周内出现。此外,患者有颈部疼痛性淋巴结肿大和咽痛。血液检查显示淋巴细胞增多以及爱泼斯坦-巴尔病毒IgG和IgM高滴度,这与传染性单核细胞增多症相符。结膜肿物活检显示混合性细胞浸润,包括淋巴细胞、浆细胞、组织细胞以及具有明显嗜酸性核仁的细胞。病变在接下来的8周内自行消退。
对于可能酷似淋巴瘤的结膜肿瘤,应考虑传染性单核细胞增多症。