• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

应激基因与物种生存。

Stress genes and species survival.

作者信息

Ray P K

机构信息

Department of Immunotechnology and Environmental Sciences, Bose Institute, Calcutta, India.

出版信息

Mol Cell Biochem. 1999 Jun;196(1-2):117-23.

PMID:10448910
Abstract

Stress genes can be ascribed to have been generated by the organism for their intrinsic urge to survive against the changing environmental odds, during the evolutionary process. This concept has been supported by a large number of reports describing individual types of phenomena. These have been reconciled and globalised in terms of their relevance in this article. Supporting evidences have been drawn from the literature which indicated that by using different types of inducer one can express heat shock proteins. Similarly, several types of stress inducers, such as calorie restriction, LPS stimulation and Staphylococcal Protein-A stimulation, it was possible to induce a wide array of biological, biochemical and immunological reactions. Such biological reactions rendered protection against toxic, carcinogenic, metabolic, as well as biological stresses induced by microorganisms. Heat shock proteins have been implicated as having a role in providing resistance to the host against different types of stressors. In this article, some mechanistic schemes have been proposed as possible pathways globalising such phenomena. A minute amount of stress inducers has been observed to have helped expression of stress resistance genes, providing increased capability to the host to protect itself against myriads of both biotic and abiotic stressors. More understanding about such phenomena would help in keeping our physiological systems vigilant and our bodies healthy, fighting out the stress-related events effectively.

摘要

应激基因可以被认为是生物体在进化过程中为了自身抵御不断变化的环境不利因素的生存本能而产生的。这一概念得到了大量描述各种现象的报告的支持。本文根据它们的相关性对这些报告进行了梳理和综合。支持证据来自文献,这些文献表明通过使用不同类型的诱导剂可以表达热休克蛋白。同样,几种类型的应激诱导剂,如热量限制、脂多糖刺激和葡萄球菌蛋白A刺激,都有可能诱导广泛的生物学、生物化学和免疫反应。这种生物学反应能够抵御由微生物引起的毒性、致癌、代谢以及生物应激。热休克蛋白被认为在赋予宿主抵抗不同类型应激源的能力方面发挥作用。在本文中,提出了一些机制方案作为使这些现象综合化的可能途径。已观察到微量的应激诱导剂有助于应激抗性基因的表达,从而增强宿主保护自身免受无数生物和非生物应激源影响的能力。对这类现象有更多的了解将有助于使我们的生理系统保持警觉,使我们的身体保持健康,有效地应对与应激相关的事件。

相似文献

1
Stress genes and species survival.应激基因与物种生存。
Mol Cell Biochem. 1999 Jun;196(1-2):117-23.
2
Methylglyoxal detoxification by a DJ-1 family protein provides dual abiotic and biotic stress tolerance in transgenic plants.DJ-1 家族蛋白对甲基乙二醛的解毒作用为转基因植物提供了对非生物和生物胁迫的双重耐受性。
Plant Mol Biol. 2017 Jul;94(4-5):381-397. doi: 10.1007/s11103-017-0613-9. Epub 2017 Apr 25.
3
The interaction of plant biotic and abiotic stresses: from genes to the field.植物生物和非生物胁迫的相互作用:从基因到田间。
J Exp Bot. 2012 Jun;63(10):3523-43. doi: 10.1093/jxb/ers100. Epub 2012 Mar 30.
4
Plant hormone-mediated regulation of stress responses.植物激素介导的应激反应调控。
BMC Plant Biol. 2016 Apr 14;16:86. doi: 10.1186/s12870-016-0771-y.
5
A step towards understanding plant responses to multiple environmental stresses: a genome-wide study.迈向理解植物对多种环境胁迫响应的一步:一项全基因组研究。
Plant Cell Environ. 2014 Sep;37(9):2024-35. doi: 10.1111/pce.12274. Epub 2014 Feb 20.
6
Comparative transcriptome profiling of Pyropia yezoensis (Ueda) M.S. Hwang & H.G. Choi in response to temperature stresses.条斑紫菜(Ueda)M.S. Hwang和H.G. Choi对温度胁迫响应的比较转录组分析
BMC Genomics. 2015 Jun 17;16(1):463. doi: 10.1186/s12864-015-1586-1.
7
Reactive short-chain leaf volatiles act as powerful inducers of abiotic stress-related gene expression.反应性短链叶片挥发物是与非生物胁迫相关基因表达的强大诱导剂。
Sci Rep. 2015 Jan 26;5:8030. doi: 10.1038/srep08030.
8
The effect of stress on udder health of dairy cows.应激对奶牛乳房健康的影响。
Onderstepoort J Vet Res. 1985 Sep;52(3):175-93.
9
Implications of heat shock/stress proteins for medicine and disease.热休克/应激蛋白对医学和疾病的影响。
J Med Invest. 1998 Feb;44(3-4):137-47.
10
Long-distance plant signaling pathways in response to multiple stressors: the gap in knowledge.响应多种应激源的长距离植物信号传导途径:知识空白
J Exp Bot. 2016 Mar;67(7):2063-79. doi: 10.1093/jxb/erw099. Epub 2016 Mar 3.

引用本文的文献

1
Optical tweezers to study single protein A/immunoglobulin G interactions at varying conditions.利用光镊研究不同条件下单蛋白A/免疫球蛋白G的相互作用。
Eur Biophys J. 2008 Jul;37(6):927-34. doi: 10.1007/s00249-008-0310-3. Epub 2008 Apr 1.
2
Fever and the heat shock response: distinct, partially overlapping processes.发热与热休克反应:不同但部分重叠的过程。
Cell Stress Chaperones. 2000 Nov;5(5):471-80. doi: 10.1379/1466-1268(2000)005<0471:fathsr>2.0.co;2.

本文引用的文献

1
The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance.谷胱甘肽S-转移酶超基因家族:谷胱甘肽S-转移酶的调控及其同工酶在癌症化学保护和耐药性中的作用。
Crit Rev Biochem Mol Biol. 1995;30(6):445-600. doi: 10.3109/10409239509083491.
2
[Regulation of cell function by level of hydration].[水合水平对细胞功能的调节]
Naturwissenschaften. 1996 Jun;83(6):264-71. doi: 10.1007/s001140050284.
3
Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis.
氧化应激反应及其在分枝杆菌对异烟肼敏感性中的作用:耻垢分枝杆菌中过氧化物对ahpC的特性及诱导作用,以及在金色分枝杆菌和结核分枝杆菌中ahpC的不表达
J Bacteriol. 1996 Jun;178(12):3641-9. doi: 10.1128/jb.178.12.3641-3649.1996.
4
Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements.通过铁反应元件对哺乳动物和果蝇柠檬酸循环酶进行翻译调控。
Proc Natl Acad Sci U S A. 1996 May 14;93(10):4925-30. doi: 10.1073/pnas.93.10.4925.
5
Avian metallothioneins: structure, regulation and evolution.鸟类金属硫蛋白:结构、调控与进化
J Nutr. 1996 Apr;126(4 Suppl):1317S-23S. doi: 10.1093/jn/126.suppl_4.1317S.
6
The complex bet promoters of Escherichia coli: regulation by oxygen (ArcA), choline (BetI), and osmotic stress.大肠杆菌复杂的甜菜碱启动子:受氧气(ArcA)、胆碱(BetI)和渗透压应激调控。
J Bacteriol. 1996 Mar;178(6):1655-62. doi: 10.1128/jb.178.6.1655-1662.1996.
7
Antitumour activity of protein A in a mouse skin model of two-stage carcinogenesis.蛋白A在小鼠皮肤两阶段致癌模型中的抗肿瘤活性。
Cancer Lett. 1996 May 15;103(1):41-7. doi: 10.1016/0304-3835(96)04188-2.
8
Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast.有丝分裂原和应激反应途径:哺乳动物和酵母中的丝裂原活化蛋白激酶级联反应和磷酸酶调节
Curr Opin Cell Biol. 1995 Dec;7(6):798-805. doi: 10.1016/0955-0674(95)80063-8.
9
The induction of gene expression in mammalian cells by radiation.辐射诱导哺乳动物细胞中的基因表达。
Semin Cancer Biol. 1993 Apr;4(2):119-28.
10
Heat shock gene expression and development. II. An overview of mammalian and avian developmental systems.
Dev Genet. 1993;14(2):87-91. doi: 10.1002/dvg.1020140202.