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通过31P核磁共振波谱法测量的人体在自愿性和电诱导等长收缩过程中的肌肉能量代谢。

Human muscle energetics during voluntary and electrically induced isometric contractions as measured by 31P NMR spectroscopy.

作者信息

Vanderthommen M, Gilles R, Carlier P, Ciancabilla F, Zahlan O, Sluse F, Crielaard J M

机构信息

Physical Medicine Department, University Hospital, Liège, Belgium.

出版信息

Int J Sports Med. 1999 Jul;20(5):279-83. doi: 10.1055/s-2007-971131.

DOI:10.1055/s-2007-971131
PMID:10452223
Abstract

Electrical stimulation (ES) and voluntary contraction (VC) were compared in the quadriceps muscle of ten male volunteers. In both modes, a workload corresponding to 20% of maximal voluntary contraction was applied during 64 isometric contraction (5.5 s)-relaxation (5.5 s) cycles. The protocols were performed in a 1.5 T whole-body magnet. The Pi/PCr ratio and the intracellular pH (pHi) were monitored by 31P NMR spectroscopy during baseline, exercise and recovery periods, in a superficial region of the vastus medialis. During baseline, the Pi/PCr ratio (0.12 vs. 0.10) and the pHi (7.01 vs. 7.00) were comparable in both conditions. During exercise, the Pi/PCr ratio was higher (0.36 vs. 0.14) and the pHi was lower (6.85 vs. 7.07) during ES than during VC. For the same external work production, these results reflect a different metabolic solicitation in the ES quadriceps than in the VC ones.

摘要

在十名男性志愿者的股四头肌中对电刺激(ES)和自主收缩(VC)进行了比较。在两种模式下,在64个等长收缩(5.5秒)-放松(5.5秒)周期中施加相当于最大自主收缩20%的工作量。实验方案在1.5T全身磁体中进行。在基线期、运动期和恢复期,通过31P核磁共振波谱法监测股内侧肌浅表区域的磷酸肌酸激酶/磷酸肌酸(Pi/PCr)比值和细胞内pH值(pHi)。在基线期,两种情况下的Pi/PCr比值(0.12对0.10)和pHi(7.01对7.00)相当。在运动期间,与VC相比,ES期间的Pi/PCr比值更高(0.36对0.14),pHi更低(6.85对7.07)。对于相同的外部功输出,这些结果反映了ES股四头肌与VC股四头肌不同的代谢需求。

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