Yasuda S, Makuuchi H, Sadahiro S, Mukai M, Ishida H, Tokunaga N, Kimura T, Tajima T, Shohtsu A
Department of Surgery, Tokai University School of Medicine, Kanagawa, Japan.
Surg Today. 1999;29(7):633-6. doi: 10.1007/BF02482990.
Increased glucose metabolism has been reported to occur in association with colorectal cancer. As positron emission tomography (PET) using [18F]fluorodeoxyglucose is able to depict hypermetabolic sites, it can therefore be used to detect colorectal cancer. A 69-year-old male patient with a recurrent solitary liver metastasis from colon cancer underwent whole-body PET which revealed high [18F]fluorodeoxyglucose uptake in the lesion. Furthermore, PET revealed peritoneal metastases that had not been detected by conventional imaging methods. Consequently, PET proved useful in helping us to avoid performing unnecessary treatment for the liver metastasis. Although it is uncertain whether early identification of recurrence can prolong survival, it may help to prevent unnecessary treatments being carried out. Thus, the application of PET in carefully selected patients could be beneficial to the management of recurrent colorectal cancer.
据报道，结直肠癌患者会出现葡萄糖代谢增加的情况。由于使用[18F]氟脱氧葡萄糖的正电子发射断层扫描（PET）能够描绘高代谢部位，因此可用于检测结直肠癌。一名69岁男性结肠癌患者出现复发性孤立性肝转移，接受了全身PET检查，结果显示病变部位[18F]氟脱氧葡萄糖摄取量高。此外，PET还发现了传统成像方法未检测到的腹膜转移。因此，PET有助于避免对肝转移进行不必要的治疗。虽然尚不确定早期发现复发是否能延长生存期，但它可能有助于避免进行不必要的治疗。因此，在精心挑选的患者中应用PET可能有利于复发性结直肠癌的管理。
