Khoury F
Department of Oral and Maxillofacial Surgery, University of Münster, Germany.
Int J Oral Maxillofac Implants. 1999 Jul-Aug;14(4):557-64.
Between 1991 and 1995, 216 sinus-lift procedures were accomplished as part of a clinical study. The study involved placing 467 implants in the atrophic posterior maxillae of 142 female and 74 male patients. The initial bone height at the implant site was between 1 and 5 mm. The implants were supported subantrally with bone block grafts harvested from the retromolar or symphysis areas of the mandible. Perforations of the maxillary sinus membrane were observed in 51 patients; these were repaired with fibrin adhesive. The spaces remaining above the bone graft were filled with various materials. A total of 28 implants failed. All the remaining implants were deemed successfully osseointegrated, based on radiographic and clinical (including periodontal health) criteria. No patients experienced maxillary sinus complications. Clinically and radiographically, the best bone regeneration was observed in those patients in whom the surgically created space was completely grafted with autogenous bone that included a high percentage of resorption-resistant cortical bone. In those patients having bone grafts harvested from the mandibular symphysis, none of their facial profiles were adversely affected; however, some patients experienced neurosensory deficits involving the mandibular anterior incisors and adjacent alveolar mucosa. Occasionally, these symptoms persisted for up to 1 year following the procedure.
1991年至1995年间,作为一项临床研究的一部分,共完成了216例鼻窦提升手术。该研究涉及为142名女性和74名男性患者的萎缩性上颌后牙区植入467颗种植体。种植体植入部位的初始骨高度在1至5毫米之间。种植体在下颌窦下方由取自下颌磨牙后区或下颌骨联合处的骨块移植支撑。51例患者观察到上颌窦膜穿孔,用纤维蛋白粘合剂修复。骨移植上方剩余的间隙用各种材料填充。共有28颗种植体失败。根据影像学和临床(包括牙周健康)标准,其余所有种植体均被认为成功实现骨整合。没有患者出现上颌窦并发症。在临床和影像学上,在那些手术创造的空间完全用自体骨移植的患者中观察到最佳的骨再生,自体骨中含有高比例的抗吸收皮质骨。在那些从下颌骨联合处获取骨移植的患者中,他们的面部轮廓均未受到不利影响;然而,一些患者出现了涉及下颌前牙和相邻牙槽黏膜的神经感觉缺陷。这些症状偶尔会在手术后持续长达1年。