Irritable bowel syndrome and lactose maldigestion in recurrent abdominal pain in childhood.
作者信息
Gremse D A, Nguyenduc G H, Sacks A I, DiPalma J A
机构信息
Department of Internal Medicine, University of South Alabama College of Medicine, Mobile 36640-0130, USA.
出版信息
South Med J. 1999 Aug;92(8):778-81. doi: 10.1097/00007611-199908000-00006.
BACKGROUND
The aim of this study was to evaluate the impact of irritable bowel syndrome (IBS) and lactose maldigestion in children with recurrent abdominal pain.
METHODS
Children who had abdominal pain associated with defecation or change in bowel habit, disordered defecation, and distension were diagnosed with IBS, and lactose maldigestion was defined by lactose breath hydrogen testing. Children with IBS were managed with increased fiber intake, while those with lactose maldigestion restricted dietary lactose. A telephone survey was conducted to determine the response to treatment.
RESULTS
The mean age of the 59 boys and 87 girls was 9.5 +/- 3.0 years. Children with IBS and lactose maldigestion had more frequent abdominal pain than children without these conditions, but they required less medication for relief of symptoms. CONCLUSIONS. Lactose maldigestion may be a contributory factor in children with IBS, and lactose avoidance in these patients may reduce medication use to relieve symptoms.
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