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乳腺手术中单次注射椎旁阻滞与全身麻醉的比较。

Single-injection paravertebral block compared to general anaesthesia in breast surgery.

作者信息

Pusch F, Freitag H, Weinstabl C, Obwegeser R, Huber E, Wildling E

机构信息

Department of Anaesthesiology, University Hospital of Vienna, Austria.

出版信息

Acta Anaesthesiol Scand. 1999 Aug;43(7):770-4. doi: 10.1034/j.1399-6576.1999.430714.x.

Abstract

BACKGROUND

Breast surgery is frequently associated with post-operative nausea, vomiting, pain and painful restricted movement. Paravertebral block may be an alternative to general anaesthesia for this type of surgery. We studied the single-injection paravertebral block at the level of T4 and report a comparison of single-injection paravertebral block to general anaesthesia for breast surgery.

METHODS

After written informed consent was obtained, 86 patients were enrolled in this prospective study. Forty-four women were randomly allocated to receive a single-injection paravertebral block at the level of T4, while 42 women received general anaesthesia. The surgical procedures varied from lumpectomy (wide local excision of a tumour) to modified radical mastectomy with axillary dissection. The block was performed according to the guidelines described by Eason and Wyatt using 0.3 ml x kg(-1) (maximum dose 150 mg) of bupivacaine 0.5%. The skin and the underlying tissues were infiltrated with local anaesthetic solution two fingers (about 3 cm) from the anatomical midline and level with the cephalad end of the vertebral spine.

RESULTS

Time for performance of blocks lasted from 4 to 9 min. Recovery from anaesthesia or sedation was shortened, while postoperative pain scores (VAS), the incidence of vomiting and the requirement for analgesics were lower in the paravertebral group. Less painful restricted movement was observed in the paravertebral block group. Paravertebral block was inadequate in 6.8% of patients. Epidural spread with paraparaesis and Horner triad was assumed in one patient.

CONCLUSION

Single-injection paravertebral block at the level of T4 represents a suitable alternative to general anaesthesia in women undergoing breast surgery.

摘要

背景

乳腺手术常伴有术后恶心、呕吐、疼痛及活动受限。椎旁阻滞可能是此类手术全麻的替代方法。我们研究了T4水平单次椎旁阻滞,并报告了乳腺手术单次椎旁阻滞与全麻的比较。

方法

获得书面知情同意后,86例患者纳入本前瞻性研究。44例女性被随机分配接受T4水平单次椎旁阻滞,42例女性接受全麻。手术方式从肿块切除术(肿瘤广泛局部切除)到改良根治性乳房切除术加腋窝清扫术不等。根据伊森和怀亚特描述的指南,使用0.5%布比卡因0.3 ml·kg⁻¹(最大剂量150 mg)进行阻滞。在距解剖学中线两指(约3 cm)且与脊柱头端平齐处,用局部麻醉溶液浸润皮肤及皮下组织。

结果

阻滞操作时间为4至9分钟。椎旁阻滞组麻醉或镇静恢复时间缩短,术后疼痛评分(视觉模拟评分法)、呕吐发生率及镇痛药需求均较低。椎旁阻滞组活动受限疼痛较轻。6.8%的患者椎旁阻滞效果不佳。1例患者疑似出现硬膜外扩散伴轻瘫及霍纳三联征。

结论

T4水平单次椎旁阻滞是乳腺手术女性患者全麻的合适替代方法。

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