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超声引导下椎旁阻滞与竖脊肌平面阻滞在改良根治性乳房切除术后镇痛效果的比较:一项随机对照试验

The comparison of the efficacy of ultrasound-guided paravertebral block versus erector spinae plane block for postoperative analgesia in modified radical mastectomy: A randomized controlled trial.

作者信息

Agarwal Shilpi, Bharati Sachidanand Jee, Bhatnagar Sushma, Mishra Seema, Garg Rakesh, Gupta Nishkarsh, Kumar Vinod, Khan Maroof Ahmad

机构信息

Department of Onco-Anaesthesia and Palliative Medicine, DR BRAIRCH, AIIMS, New Delhi, India.

Department of Biostatistics, AIIMS, New Delhi, India.

出版信息

Saudi J Anaesth. 2021 Apr-Jun;15(2):137-143. doi: 10.4103/sja.sja_990_20. Epub 2021 Apr 1.

Abstract

INTRODUCTION

The ultrasound (US)-guided erector spinae plane (ESP) block is a new regional anesthetic technique that offers significant advantages over paravertebral block as it is easy and safe to perform. We aim to compare the efficacy of US-guided paravertebral block with ESP block for postoperative analgesia in modified radical mastectomy (MRM).

METHODS

Eighty female patients of age group 18-70 years, belonging to physical status American Society of Anesthesiologists (ASA) I and II, undergoing MRM were included in the study. In Group P, patients received paravertebral block and in Group E, patients received ESP block before induction of general anesthesia. Both the groups received 0.5% 20 mL ropivacaine. The time to first rescue analgesia and total doses of rescue analgesics were recorded in the postoperative period. Numeric Rating Scale (NRS) scores at 0 min, 30 min, 1 h, 2 h, 6 h, 12 h, and 24 h were noted, and patient satisfaction was evaluated at 24 h. Unpaired -test or the Mann-Whitney U test was used to compare quantitative variables while Chi-square test or Fisher's exact test was used to compare qualitative variables.

RESULTS

The time for the first analgesic request was 232.5 min (140-1200) in ESP group as compared to paravertebral group in which the duration was 205 min (135-1190) ( value = 0.29). The total dose of rescue analgesics and NRS scores in postoperative period were comparable. However, the time to perform ESP block was significantly shorter than that of paravertebral block.

CONCLUSION

ESP block can be used as a safe and easy to perform alternative analgesic technique over paravertebral block in breast cancer surgeries.

摘要

引言

超声(US)引导下竖脊肌平面(ESP)阻滞是一种新的区域麻醉技术,与椎旁阻滞相比具有显著优势,因为其操作简便且安全。我们旨在比较US引导下椎旁阻滞与ESP阻滞在改良根治性乳房切除术(MRM)术后镇痛中的效果。

方法

纳入80例年龄在18 - 70岁、美国麻醉医师协会(ASA)身体状况分级为I级和II级、接受MRM手术的女性患者。在P组,患者在全身麻醉诱导前接受椎旁阻滞;在E组,患者接受ESP阻滞。两组均接受0.5% 20 mL罗哌卡因。记录术后首次补救镇痛时间和补救镇痛药的总剂量。记录术后0分钟、30分钟、1小时、2小时、6小时、12小时和24小时的数字评定量表(NRS)评分,并在24小时时评估患者满意度。采用非配对t检验或曼 - 惠特尼U检验比较定量变量,采用卡方检验或费舍尔精确检验比较定性变量。

结果

ESP组首次镇痛需求时间为232.5分钟(140 - 1200),而椎旁组为205分钟(135 - 1190)(P值 = 0.29)。术后补救镇痛药的总剂量和NRS评分相当。然而,实施ESP阻滞的时间明显短于椎旁阻滞。

结论

在乳腺癌手术中,ESP阻滞可作为一种安全且操作简便的替代镇痛技术用于替代椎旁阻滞。

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