Hochwald S N, Dobryansky M B A, Rofsky N M, Naik K S, Shamamian P, Coppa G, Marcus S G
Department of Surgery and Radiology, New York University Medical Center, New York, New York 10016, USA.
J Gastrointest Surg. 1998 Nov-Dec;2(6):573-9. doi: 10.1016/s1091-255x(98)80059-0.
Accurate common bile duct (CBD) imaging in patients with biliary calculi is an important determinant of specific therapy. Noninvasive methods to evaluate calculi in the CBD have limited accuracy and rely mainly on ultrasonography and computed tomography. Magnetic resonance cholangiopancreatography (MRCP) is a new noninvasive modality available to evaluate the biliary system. This study was undertaken to assess the accuracy of MRCP in predicting the presence or absence of CBD stones in patients at increased risk for choledocholithiasis. The medical records of 48 patients with a final diagnosis of biliary calculous disease undergoing MRCP between November 1995 and April 1997 were retrospectively reviewed. Three groups were identified: choledocholithiasis (n = 19), gallstone pancreatitis (n 5 11), and uncomplicated cholelithiasis (n = 18). In all patients the presence or absence of CBD calculi, as determined by MRCP, was correlated with the final diagnosis obtained from endoscopic retrograde cholangiopancreatography (ERCP) (n = 19), intraoperative cholangiography (n = 6), CBD exploration (n = 13), or clinical follow-up (n = 10). Sensitivity, specificity, and accuracy of MRCP were determined. The major clinical indications for MRCP in the 48 patients ware abnormal liver function tests followed by hyperamylasemia. Twenty patients were diagnosed with CBD stones and 28 were not. MRCP correctly predicted the presence of CBD stones in 19 of 20 patients and failed to detect CBD stones in one patient with gallstone pancreatitis. MRCP incorrectly predicted the presence of CBD stones in 3 of 28 patients ultimately found to have gallstones and no CBD stones. MRCP correctly predicted the absence of CBD stones in the other 25 patients including 10 patients with gallstone pancreatitis. Overall, MRCP had a sensitivity of 95%, a specificity of 89%, and an accuracy of 92%. MRCP is an accurate, noninvasive test for evaluating the CBD duct for the presence or absence of calculi in patients suspected of having CBD stones. Our data support the use of MRCP in the preoperative evaluation of these patients as findings may influence therapeutic decisions.
准确成像胆管结石患者的胆总管是特定治疗的重要决定因素。评估胆总管结石的非侵入性方法准确性有限,主要依赖超声检查和计算机断层扫描。磁共振胰胆管造影(MRCP)是一种可用于评估胆道系统的新型非侵入性检查方法。本研究旨在评估MRCP在预测胆总管结石高危患者胆总管结石存在与否方面的准确性。对1995年11月至1997年4月期间48例最终诊断为胆石症并接受MRCP检查的患者的病历进行回顾性分析。分为三组:胆总管结石(n = 19)、胆石性胰腺炎(n = 11)和单纯胆囊结石(n = 18)。在所有患者中,由MRCP确定的胆总管结石的存在与否与通过内镜逆行胰胆管造影(ERCP)(n = 19)、术中胆管造影(n = 6)、胆总管探查(n = 13)或临床随访(n = 10)获得的最终诊断相关。确定了MRCP的敏感性、特异性和准确性。48例患者进行MRCP的主要临床指征是肝功能检查异常,其次是高淀粉酶血症。20例患者诊断为胆总管结石,28例未诊断出。MRCP在20例患者中的19例正确预测了胆总管结石的存在,在1例胆石性胰腺炎患者中未能检测出胆总管结石。在最终发现有胆囊结石而无胆总管结石的28例患者中,MRCP错误地预测了3例存在胆总管结石。MRCP在包括10例胆石性胰腺炎患者在内的其他25例患者中正确预测了无胆总管结石。总体而言,MRCP的敏感性为95%,特异性为89%,准确性为92%。对于怀疑有胆总管结石的患者,MRCP是一种准确的非侵入性检查,用于评估胆总管是否存在结石。我们的数据支持在这些患者的术前评估中使用MRCP,因为检查结果可能会影响治疗决策。