Richer S
Optometry Section/Operative and Invasive Procedures, DVA Medical Center, North Chicago, Illinois, USA.
J Am Optom Assoc. 1999 Jan;70(1):24-36.
A description and justification for using a standardized clinical low-cost, "low-technology," ocular and systemic "ARMD work-up" protocol was presented in the methods paper (Part I).
Fourteen male patients (70 +/- 9 years), receiving 0.73 +/- 0.45 portions of dark-green, leafy vegetables/day base intake, were placed on an additional portion of 5 ounces sauted spinach 4 to 7 times per week or lutein-based antioxidant (three patients). Detailed "ARMD work-up" data for six of these patients and summary pilot (case series) environmental intervention data are presented.
One, Patients demonstrated short-term positive effects in visual function in one or both eyes with this mild therapeutic approach: Amsler grid (87%); Snellen Acuity (71%); Contrast sensitivity (92%); SKILL (65%); Glare recovery (69%); and Activities of Daily Vision Subscale (60%); Two, There was no obvious correlation between ophthalmoscopic appearance of the retina and visual outcome; and Three, Patient symptoms did not necessarily correlate with observed changes in visual function.
The approach to atrophic ARMD presented here warrants informal practitioner replication and formal randomized prospective clinical case-control evaluation.
在方法篇论文（第一部分）中介绍了使用标准化临床低成本、“低技术”的眼部及全身“年龄相关性黄斑变性检查”方案的描述及理由。
14名男性患者（70±9岁），每天摄入0.73±0.45份深绿色叶菜类蔬菜作为基础摄入量，每周4至7次额外摄入5盎司炒菠菜或叶黄素类抗氧化剂（3名患者）。呈现了其中6名患者的详细“年龄相关性黄斑变性检查”数据以及总结性试点（病例系列）环境干预数据。
其一，采用这种温和治疗方法后，患者一只或两只眼睛的视觉功能出现短期积极效果：阿姆斯勒方格表检查（87%）；斯内伦视力表检查（71%）；对比敏感度检查（92%）；SKILL检查（65%）；眩光恢复检查（69%）；日常视觉子量表活动检查（60%）；其二，视网膜的检眼镜外观与视觉结果之间无明显相关性；其三，患者症状不一定与观察到的视觉功能变化相关。
此处提出的萎缩性年龄相关性黄斑变性治疗方法值得临床医生进行非正式重复试验以及正式的随机前瞻性临床病例对照评估。
